AVC

Unité neurovasculaire (UNV) - Hôpital de la Timone

  • Tél. secrétariat : 04 91 38 59 26
  • Mail : unv@ap-hm.fr
  • Fax : 04 91 38 45 68

 

Equipe
medecins: 
  • Pr Laurent SUISSA
  • Dr Abdelmalek BRINET
  • Dr Émilie DOCHE
  • Dr Cécile DULAU-METRAS
  • Dr Nadia LAKSIRI
  • Dr Ophelie OSMAN
  • Dr Roxane PERES
  • Dr Caroline REY
  • Dr Emmanuelle ROBINET BORGOMANO
  • Dr Salome SNYMAN
  • Dr Romy ZOGHAIB

 

Cadres de santé : 

  • Mmes Sophie FERNANDEZ & Véronka SZITTYA

 

​Infirmière de pratique avancée : 

  • Julia GIORDANO

 

Infirmière coordinatrice : 

  • Charlotte MORET

 

Psychologue : 

  • Noa BOTTON

 

Orthophoniste : 

  • Raphaëlle LESIGNE
Consultations
Consultations: 

(Avis neurovasculaires ; Suivi post-AVC)
 

Pour toute demande de consultation neurovasculaire, veuillez nous adresser un courrier de votre médecin avec vos coordonnées, par mail (unv@ap-hm.fr) ou Fax (04 91 38 45 68)

En cas de demande de consultation urgente, votre médecin doit contacter un médecin du service via le secrétariat (Tél. 04 91 38 59 26)

En cas d'urgence médicale, contacter le SAMU au 15 ou 112 

 

Hôpitaux Universitaires de Marseille Timone
Disciplines: 
Infarctus cérébral
AVC
Neurovasculaire
Stroke Center
Thrombolyse
Thrombectomie mécanique
Spécialités: 
AVC
Accident vasculaire cérébral
Accident Ischémique transitoire
AIT
Thrombose veineuse cérébrale
Maladies vasculaires rares du cerveau et de l’œil
Chefs de services: 
SUISSA Laurent
Hôpital secteur: 
Services adultes
Pathologies
Pathologies: 
  • Accident vasculaire cérébral ischémique (AVC ischémique)
  • Accident vasculaire cérébral hémorragique (AVC hémorragique)
  • Accident Ischémique transitoire (AIT)
  • Thrombose veineuse cérébrale
  • Maladies vasculaires rares du cerveau et de l’œil
Techniques et traitements
Techniques et traitements: 
  • Prise en charge en urgence des Accidents Vasculaires Cérébraux (AVC)
  • Prise en charge des Accidents Ischémiques Transitoires
  • Soins Intensifs Neurovasculaires
  • Techniques de recanalisation cérébrale (Thrombolyse, thrombectomie)
  • Centre de compétence pour les maladies neurovasculaires rares
  • Centre de recours Neurovasculaire PACA Ouest
  • Suivi des affections neurovasculaires chroniques
  • Doppler des troncs supra-aortiques et Trans crânien
Publications
Publications: 
  • Doche, E ; Sulowski, C ; Guigonis, JM ; Graslin, F ; Casolla, B ; Hak, JF & al , How clot composition influences fibrinolysis in the acute phase of stroke: a proteomic study of cerebral thrombi., Stroke, 2024, 
  • Costalat, V ; Jovin, TG ; Albucher, JF ; Cognard, C ; Henon, H ; Nouri, N & al , Trial of Thrombectomy for Stroke with a Large Infarct of Unrestricted Size., N Engl J Med, 2024, 390, 1677-1689
  • Plourde, G ; Roumes, H ; Suissa, L ; Hirt, L ; Doche, É ; Pellerin, L & al , Neuroprotective effects of lactate and ketone bodies in acute brain injury., J Cereb Blood Flow Metab, 2024, 44, 1078-1088
  • Tournier, L ; Cortese, J ; Consoli, A ; Spelle, L ; Marnat, G ; Sarov, M & al , Mechanical thrombectomy in basilar artery occlusions: impact of first-line strategy as a function of the occlusion level., J Neurointerv Surg, 2024, ,
  • Bobot, M ; Hak, JF ; Casolla, B ; Dehondt, JD ; Burtey, S ; Doche, E & al , Acute and chronic kidney dysfunction and prognosis following thrombectomy for ischemic stroke., Am J Nephrol, 2024, ,
  • Seners, P ; Khyheng, M ; Labreuche, J ; Lapergue, B ; Pico, F , Inter-hospital transfer for thrombectomy: transfer time is brain., Eur J Neurol, 2024, 31, e16276
  • Mazighi, M ; Köhrmann, M ; Lemmens, R ; Lyrer, PA ; Molina, CA ; Richard, S & al , Safety and efficacy of platelet glycoprotein VI inhibition in acute ischaemic stroke (ACTIMIS): a randomised, double-blind, placebo-controlled, phase 1b/2a trial., Lancet Neurol, 2024, 23, 157-167
  • El Harake, S ; Doche, E ; Bertolino, J ; Laksiri, N ; Bartoli, MA ; Leclercq, B & al , Symptomatic Carotid Free-Floating Thrombus: About Management of 50 Cases in a Referral Neurovascular Center., J Clin Med, 2023, 12,
  • Olindo, S ; Gaillard, N ; Chausson, N ; Turpinat, C ; Dargazanli, C ; Bourgeois-Beauvais, Q & al , Clinical, imaging, and management features of symptomatic carotid web: Insight from CAROWEB registry., Int J Stroke, 2024, 19, 180-188
  • Chalos, V ; Venema, E ; Mulder, MJHL ; Roozenbeek, B ; Steyerberg, EW ; Wermer, MJH & al , Development and Validation of a Postprocedural Model to Predict Outcome After Endovascular Treatment for Ischemic Stroke., JAMA Neurol, 2023, 80, 940-8
  • Palazzo, P ; Padlina, G ; Dobrocky, T ; Strambo, D ; Seners, P ; Mechtouff, L & al , Relevance of National Institutes of Health Stroke Scale subitems for best revascularization therapy in minor stroke patients with large vessel occlusion: An observational multicentric study., Eur J Neurol, 2023, 30, 3741-3750
  • Horowitz, T ; Doche, E ; Philip, M ; Cammilleri, S ; Suissa, L ; Guedj, E , Regional brain glucose metabolism is differentially affected by ketogenic diet: a human semiquantitative positron emission tomography., Eur J Nucl Med Mol Imaging, 2023, 50, 2047-2055
  • Bobot, M ; Suissa, L ; Hak, JF ; Burtey, S ; Guillet, B ; Hache, G , Kidney disease and stroke: epidemiology and potential mechanisms of susceptibility., Nephrol Dial Transplant, 2023, 38, 1940-1951
  • Marnat, G ; Holay, Q ; Darcourt, J ; Desilles, JP ; Obadia, M ; Viguier, A & al , Dual-layer carotid stenting for symptomatic carotid web: Results from the Caroweb study., J Neuroradiol, 2023, 50, 444-448
  • Snyman, S ; Seder, E ; David-Muller, M ; Klein, V ; Doche, E ; Suissa, L & al , Atrial Fibrillation Detected by Implantable Monitor in Embolic Stroke of Undetermined Source: A New Clinical Entity., J Clin Med, 2022, 11,
  • Kapadia, SR ; Makkar, R ; Leon, M ; Abdel-Wahab, M ; Waggoner, T ; Massberg, S & al , Cerebral Embolic Protection during Transcatheter Aortic-Valve Replacement., N Engl J Med, 2022, 387, 1253-1263
  • Boulenoir, N ; Turc, G ; Ter Schiphorst, A ; Heldner, MR ; Strambo, D ; Laksiri, N & al , Should Patients With Acute Minor Ischemic Stroke With Isolated Internal Carotid Artery Occlusion Be Thrombolysed?, Stroke, 2022, 53, 3304-3312
  • Seners, P ; Arquizan, C ; Fontaine, L ; Ben Hassen, W ; Heldner, MR ; Strambo, D & al , Perfusion Imaging and Clinical Outcome in Acute Minor Stroke With Large Vessel Occlusion., Stroke, 2022, 53, 3429-3438
  • Chau, Y ; Arnoffi, P ; Suissa, L ; Lachaud, S ; Varnier, Q ; Sédat, J , Use of the Rocket Technique after Failure of the Direct Aspiration First-Pass Technique in Acute Stroke Thrombectomy., J Vasc Interv Radiol, 2022, 33, 572-577.e1
  • Dehondt, JD ; Holay, Q ; Brohee, S ; Mourre, H ; Hak, JF ; Osman, O & al , Diabetes is an Independent Growth Factor of Ischemic Stroke During Reperfusion Phase Leading to Poor Clinical Outcome., J Stroke Cerebrovasc Dis, 2022, 31, 106477
  • Ter Schiphorst, A ; Peres, R ; Dargazanli, C ; Blanc, R ; Gory, B ; Richard, S & al , Endovascular treatment of ischemic stroke due to isolated internal carotid artery occlusion: ETIS registry data analysis., J Neurol, 2022, 269, 4383-4395
  • McDonough, RV ; Ospel, JM ; Majoie, CBLM ; Saver, JL ; White, P ; Dippel, DWJ & al , Clinical outcome of patients with mild pre-stroke morbidity following endovascular treatment: a HERMES substudy., J Neurointerv Surg, 2023, 15, 214-220
  • Forestier, G ; Escalard, S ; Sedat, J ; Saleme, S ; Mounayer, C ; Montcuquet, A & al , Non-ischemic cerebral enhancing lesions after thrombectomy: a multicentric retrospective French national registry., Neuroradiology, 2022, 64, 1037-1042
  • Kerleroux, B ; Benzakoun, J ; Janot, K ; Dargazanli, C ; Eraya, DD ; Ben Hassen, W & al , Relevance of Brain Regions'' Eloquence Assessment in Patients With a Large Ischemic Core Treated With Mechanical Thrombectomy., Neurology, 2021, 97, e1975-e1985
  • Suissa, L ; Guigonis, JM ; Graslin, F ; Robinet-Borgomano, E ; Chau, Y ; Sedat, J & al , Combined Omic Analyzes of Cerebral Thrombi: A New Molecular Approach to Identify Cardioembolic Stroke Origin., Stroke, 2021, 52, 2892-2901
  • Calmettes, J ; Peres, R ; Goncalves, B ; Varlan, D ; Turc, G ; Obadia, M & al , Clinical Outcome of Acute Ischemic Strokes in Patients with COVID-19., Cerebrovasc Dis, 2021, 50, 412-419
  • Suissa, L ; Kotchetkov, P ; Guigonis, JM ; Doche, E ; Osman, O ; Pourcher, T & al , Ingested Ketone Ester Leads to a Rapid Rise of Acetyl-CoA and Competes with Glucose Metabolism in the Brain of Non-Fasted Mice., Int J Mol Sci, 2021, 22,
  • Seners, P ; Ben Hassen, W ; Lapergue, B ; Arquizan, C ; Heldner, MR ; Henon, H & al , Prediction of Early Neurological Deterioration in Individuals With Minor Stroke and Large Vessel Occlusion Intended for Intravenous Thrombolysis Alone., JAMA Neurol, 2021, 78, 321-328
  • Seners, P ; Dargazanli, C ; Piotin, M ; Sablot, D ; Bracard, S ; Niclot, P & al , Intended Bridging Therapy or Intravenous Thrombolysis Alone in Minor Stroke With Basilar Artery Occlusion., Stroke, 2021, 52, 699-702
  • Suissa, L ; Guigonis, JM ; Graslin, F ; Doche, E ; Osman, O ; Chau, Y & al , Metabolome of Cerebral Thrombi Reveals an Association between High Glycemia at Stroke Onset and Good Clinical Outcome., Metabolites, 2020, 10,
  • Boulenoir, N ; Turc, G ; Henon, H ; Laksiri, N ; Mounier-Véhier, F ; Girard Buttaz, I & al , Early neurological deterioration following thrombolysis for minor stroke with isolated internal carotid artery occlusion., Eur J Neurol, 2021, 28, 479-490
  • Kerleroux, B ; Janot, K ; Dargazanli, C ; Daly-Eraya, D ; Ben-Hassen, W ; Zhu, F & al , Perfusion Imaging to Select Patients with Large Ischemic Core for Mechanical Thrombectomy., J Stroke, 2020, 22, 225-233
  • Zhu, F ; Hossu, G ; Soudant, M ; Richard, S ; Achit, H ; Beguinet, M & al , Effect of emergent carotid stenting during endovascular therapy for acute anterior circulation stroke patients with tandem occlusion: A multicenter, randomized, clinical trial (TITAN) protocol., Int J Stroke, 2021, 16, 342-348
  • Seners, P ; Perrin, C ; Lapergue, B ; Henon, H ; Debiais, S ; Sablot, D & al , Bridging Therapy or IV Thrombolysis in Minor Stroke with Large Vessel Occlusion., Ann Neurol, 2020, 88, 160-169
  • Suissa, L ; Panicucci, E ; Perot, C ; Romero, G ; Gazzola, S ; Laksiri, N & al , Effect of hyperglycemia on stroke outcome is not homogeneous to all patients treated with mechanical thrombectomy., Clin Neurol Neurosurg, 2020, 194, 105750
  • Osman, O ; Labrune, P ; Reiner, P ; Sarov, M ; Nasser, G ; Riant, F & al , Leukoencephalopathy with calcifications and cysts (LCC): 5 cases and literature review., Rev Neurol (Paris), 2020, 176, 170-179
  • Suissa, L ; Flachon, V ; Guigonis, JM ; Olivieri, CV ; Burel-Vandenbos, F ; Guglielmi, J & al , Urinary ketone body loss leads to degeneration of brain white matter in elderly SLC5A8-deficient mice., J Cereb Blood Flow Metab, 2020, 40, 1709-1723
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