Services adultes

Recherches :

CRMBM-CEMEREM UMRCNRS7339  https://crmbm.univ-amu.fr/

• Épidémiologie, Génétique, Immunologie, Neuropsychologie de la SEP et des affections inflammatoires du système nerveux central
• Techniques d’IRM conventionnelles et avancées appliquées aux affections inflammatoires du système nerveux central
• Développement de nouvelles thérapeutiques dans la SEP et les affections inflammatoires du système nerveux central. Essais cliniques et thérapeutiques dans la SEP et les affections inflammatoires du système nerveux central (centre investigateur et coordonnateurs au niveau national et international)
• Laboratoire de recherche d’affiliation du service : CRMBM CEMEREM UMRCNRS7339 impliqué dans l’imagerie IRM en particulier à très haut champ (IRM 7T)

Accéder à nos publications :

• https://pubmed.ncbi.nlm.nih.gov/?term=Pelletier+J+OR+Audoin+B+OR+Maarouf+A+AND+Marseille

Les maladies neurodégénératives du système nerveux central sont des pathologies dont l’incidence croît dans nos sociétés industrialisées. L’amélioration de leur prise en charge est devenue un enjeu crucial de santé publique. Mieux les traiter nécessite cependant de mieux les comprendre et de mieux les individualiser.

Les activités de recherche visent ainsi à : comprendre les déterminants biologiques de ces maladies ; développer des outils diagnostiques discriminants, cliniques, radiologiques et biologiques ; développer des molécules ciblant les mécanismes biologiques de ces maladies et évaluer leurs effets.

Recherches et publications récentes :

Morin A, Pressat-Laffouilhere T, Sarazin M, Lagarde J, Roue-Jagot C, Olivieri P, Paquet C, Cognat E, Dumurgier J, Pasquier F, Lebouvier T, Ceccaldi M, Godefroy O, Martinaud O, Grosjean J, Zarea A, Maltête D, Wallon D. Telemedicine in French Memory Clinics During the COVID-19 Pandemic. J Alzheimers Dis. 2021 in press.

Guedj E, Campion JY, Horowitz T, Barthelemy F, Cammilleri S, Ceccaldi M. The impact of COVID-19 lockdown on brain metabolism. Hum Brain Mapp 2022;43:593-597.

Barbier M, Camuzat A, Hachimi KE, Guegan J, Rinaldi D, Lattante S, Houot M, Sánchez-Valle R, Sabatelli M, Antonell A, Molina-Porcel L, Clot F, Couratier P, van der Ende E, van der Zee J, Manzoni C, Camu W, Cazeneuve C, Sellal F, Didic M, Golfier V, Pasquier F, Duyckaerts C, Rossi G, Bruni AC, Alvarez V, Gómez-Tortosa E, de Mendonça A, Graff C, Masellis M, Nacmias B, Oumoussa BM, Jornea L, Forlani S; French clinical and genetic Research network on FTLD/FTLD-ALS and PREVDEMALS, The International Frontotemporal Dementia Genomics Consortium, The European Early Onset Dementia (EU -EOD) Consortium, Brainbank Neuro-CEB Neuropathology Network, Neurological Tissue Bank of the Biobank Hospital Clinic-IDIBAPS, Van Deerlin V, Rohrer JD, Gelpi E, Rademakers R, Van Swieten J, Le Guern E, Van Broeckhoven C, Ferrari R, Génin E, Brice A, Le Ber I. SLITRK2, an X-linked modifier of the age at onset in C9orf72 frontotemporal lobar degeneration. Brain. 2021 Oct 22;144(9):2798-2811.

Jansen WJ, Janssen O, Tijms BM, Vos SJB, Ossenkoppele R, Visser PJ; Amyloid Biomarker Study Group, Aarsland D, Alcolea D, Altomare D, von Arnim C, Baiardi S, Baldeiras I, Barthel H, Bateman RJ, Van Berckel B, Binette AP, Blennow K, Boada M, Boecker H, Bottlaender M, den Braber A, Brooks DJ, Van Buchem MA, Camus V, Carill JM, Cerman J, Chen K, Chételat G, Chipi E, Cohen AD, Daniels A, Delarue M, Didic M, Drzezga A, Dubois B, Eckerström M, Ekblad LL, Engelborghs S, Epelbaum S, Fagan AM, Fan Y, Fladby T, Fleisher AS, Van der Flier WM, Förster S, Fortea J, Frederiksen KS, Freund-Levi Y, Frings L, Frisoni GB, Fröhlich L, Gabryelewicz T, Gertz HJ, Gill KD, Gkatzima O, Gómez-Tortosa E, Grimmer T, Guedj E, Habeck CG, Hampel H, Handels R, Hansson O, Hausner L, Hellwig S, Heneka MT, Herukka SK, Hildebrandt H, Hodges J, Hort J, Huang CC, Iriondo AJ, Itoh Y, Ivanoiu A, Jagust WJ, Jessen F, Johannsen P, Johnson KA, Kandimalla R, Kapaki EN, Kern S, Kilander L, Klimkowicz-Mrowiec A, Klunk WE, Koglin N, Kornhuber J, Kramberger MG, Kuo HC, Van Laere K, Landau SM, Landeau B, Lee DY, de Leon M, Leyton CE, Lin KJ, Lleó A, Löwenmark M, Madsen K, Maier W, Marcusson J, Marquié M, Martinez-Lage P, Maserejian N, Mattsson N, de Mendonça A, Meyer PT, Miller BL, Minatani S, Mintun MA, Mok VCT, Molinuevo JL, Morbelli SD, Morris JC, Mroczko B, Na DL, Newberg A, Nobili F, Nordberg A, Olde Rikkert MGM, de Oliveira CR, Olivieri P, Orellana A, Paraskevas G, Parchi P, Pardini M, Parnetti L, Peters O, Poirier J, Popp J, Prabhakar S, Rabinovici GD, Ramakers IH, Rami L, Reiman EM, Rinne JO, Rodrigue KM, Rodríguez-Rodriguez E, Roe CM, Rosa-Neto P, Rosen HJ, Rot U, Rowe CC, Rüther E, Ruiz A, Sabri O, Sakhardande J, Sánchez-Juan P, Sando SB, Santana I, Sarazin M, Scheltens P, Schröder J, Selnes P, Seo SW, Silva D, Skoog I, Snyder PJ, Soininen H, Sollberger M, Sperling RA, Spiru L, Stern Y, Stomrud E, Takeda A, Teichmann M, Teunissen CE, Thompson LI, Tomassen J, Tsolaki M, Vandenberghe R, Verbeek MM, Verhey FRJ, Villemagne V, Villeneuve S, Vogelgsang J, Waldemar G, Wallin A, Wallin ÅK, Wiltfang J, Wolk DA, Yen TC, Zboch M, Zetterberg H. Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum. JAMA Neurol 2022 Jan 31. doi: 10.1001/jamaneurol.2021.5216.

Mulatero M, Boucekine M, Felician O, Boussen S, Kaplanski G, Rossi P, Parola P, Stein A, Brouqui P, Lagier JC, Leone M, Kaphan E. Herpetic encephalitis: which treatment for which body weight? J Neurol. 2022 Jan 31. doi: 10.1007/s00415-022-10981-8.

Frison E, Proust-Lima C, Mangin JF, Habert MO, Bombois S, Ousset PJ, Pasquier F, Hanon O, Paquet C, Gabelle A, Ceccaldi M, Annweiler C, Krolak-Salmon P, Béjot Y, Belin C, Wallon D, Sauvee M, Beaufils E, Bourdel-Marchasson I, Jalenques I, Chupin M, Chêne G, Dufouil C; MEMENTO Cohort Study Group. Diabetes Mellitus and Cognition: Pathway Analysis in the MEMENTO Cohort. Neurology 2021;97:e836-e848.

Boccardi M, Monsch AU, Ferrari C, Altomare D, Berres M, Bos I, Buchmann A, Cerami C, Didic M, Festari C, Nicolosi V, Sacco L, Aerts L, Albanese E, Annoni JM, Ballhausen N, Chicherio C, Démonet JF, Descloux V, Diener S, Ferreira D, Georges J, Gietl A, Girtler N, Kilimann I, Klöppel S, Kustyniuk N, Mecocci P, Mella N, Pigliautile M, Seeher K, Shirk SD, Toraldo A, Brioschi-Guevara A, Chan KCG, Crane PK, Dodich A, Grazia A, Kochan NA, de Oliveira FF, Nobili F, Kukull W, Peters O, Ramakers I, Sachdev PS, Teipel S, Visser PJ, Wagner M, Weintraub S, Westman E, Froelich L, Brodaty H, Dubois B, Cappa SF, Salmon D, Winblad B, Frisoni GB, Kliegel M; Consortium for the Harmonization of Neuropsychological Assessment for Neurocognitive Disorders. Harmonizing neuropsychological assessment for mild neurocognitive disorders in Europe. Alzheimers Dement. 2022;18:29-42.

Saracino D, Ferrieux S, Noguès-Lassiaille M, Houot M, Funkiewiez A, Sellami L, Deramecourt V, Pasquier F, Couratier P, Pariente J, Géraudie A, Epelbaum S, Wallon D, Hannequin D, Martinaud O, Clot F, Camuzat A, Bottani S, Rinaldi D, Auriacombe S, Sarazin M, Didic M, Claire BB, Thauvin-Robinet C, Lagarde J, Roué-Jagot C, Sellal F, Gabelle A, Etcharry-Bouyx F, Morin A, Coppola C, Levy R, Dubois B, Brice A, Colliot O, Gorno-Tempini ML, Teichmann M, Migliaccio R, Le Ber I; French research network on FTD/FTD-ALS. Primary Progressive Aphasia Associated With GRN Mutations: New Insights Into the Non-amyloid Logopenic Variant. Neurology. 2021 97:e88-e102.

Arbabyazd LM, Lombardo D, Blin O, Didic M, Battaglia D, Jirsa V. Dynamic Functional Connectivity as a complex random walk: Definitions and the dFCwalk toolbox. MethodsX. 2020 Dec 1;7:101168.

Guedj E, Lazarini F, Morbelli S, Ceccaldi M, Hautefort C, Kas A, Radulesco T, Salmon-Ceron D, Eldin C. Long COVID and the brain network of Proust's madeleine: targeting the olfactory pathway. Clin Microbiol Infect. 2021 in press.

Chamberlain JD, Rouanet A, Dubois B, Pasquier F, Hanon O, Gabelle A, Ceccaldi M, Krolak-Salmon P, Béjot Y, Godefroy O, Wallon D, Gentric A, Chêne G, Dufouil C; Memento Study group. Investigating the association between cancer and the risk of dementia: Results from the Memento cohort. Alzheimers Dement. 2021 in press.

Pann A, Bonnard M, Felician O, Romaiguère P. The Extrastriate Body Area and identity processing: An fMRI guided TMS study. Physiol Rep. 2021 Apr;9(8):e14711.

Lambert I, Tramoni-Negre E, Lagarde S, Pizzo F, Trebuchon-Da Fonseca A, Bartolomei F, Felician O. Accelerated long-term forgetting in focal epilepsy: Do interictal spikes during sleep matter? Epilepsia 2021, 62:563-569.

Guedj E, Campion JY, Dudouet P, Kaphan E, Bregeon F, Tissot-Dupont H, Guis S, Barthelemy F, Habert P, Ceccaldi M, Million M, Raoult D, Cammilleri S, Eldin C. 18F-FDG brain PET hypometabolism in patients with long COVID. Eur J Nucl Med Mol Imaging. 2021 Jan 26:1-11.

Garibotto V, Trombella S, Antelmi L, Bosco P, Redolfi A, Tabouret-Viaud C, Rager O, Gold G, Giannakopoulos P, Morbelli S, Nobili F, Perneczky R, Didic M, Guedj E, Drzezga A, Ossenkoppele R, Berckel BV, Ratib O, Frisoni GB. A Comparison of Two Statistical Mapping Tools for Automated Brain FDG-PET Analysis in Predicting Conversion to Alzheimer's Disease in Subjects with Mild Cognitive Impairment. Curr Alzheimer Res, 2021 in press.

Tilsley PA, Romaiguère P, Tramoni E, Felician O, Sarlegna FR. Interlimb transfer of reach adaptation does not require an intact corpus callosum: Evidence from patients with callosal lesions and agenesis. eNeuro, 2021, 8(4):ENEURO.0190-20.2021.

Frederiksen KS, Nielsen TR, Appollonio I, Andersen BB, Riverol M, Boada M, Ceccaldi M, Dubois B, Engelborghs S, Frölich L, Hausner L, Gabelle A, Gabryelewicz T, Grimmer T, Hanseeuw B, Hort J, Hugon J, Jelic V, Koivisto A, Kramberger MG, Lebouvier T, Lleó A, de Mendonça A, Nobili F, Ousset PJ, Perneczky R, Olde Rikkert M, Robinson D, Rouaud O, Sánchez E, Santana I, Scarmeas N, Sheardova K, Sloan S, Spiru L, Stefanova E, Traykov L, Yener G, Waldemar G. Biomarker counseling, disclosure of diagnosis and follow-up in patients with mild cognitive impairment: A European Alzheimer's disease consortium survey. Int J Geriatr Psychiatry 2021 Feb;36(2):324-333.

Ribaldi F, Altomare D, Jovicich J, Ferrari C, Picco A, Pizzini FB, Soricelli A, Mega A, Ferretti A, Drevelegas A, Bosch B, Müller BW, Marra C, Cavaliere C, Bartrés-Faz D, Nobili F, Alessandrini F, Barkhof F, Gros-Dagnac H, Ranjeva JP, Wiltfang J, Kuijer J, Sein J, Hoffmann KT, Roccatagliata L, Parnetti L, Tsolaki M, Constantinidis M, Aiello M, Salvatore M, Montalti M, Caulo M, Didic M, Bargallo N, Blin O, Rossini PM, Schonknecht P, Floridi P, Payoux P, Visser PJ, Bordet R, Lopes R, Tarducci R, Bombois S, Hensch T, Fiedler U, Richardson JC, Frisoni GB, Marizzoni M. Accuracy and reproducibility of automated white matter hyperintensities segmentation with lesion segmentation tool: A European multi-site 3T study. Magn Reson Imaging. 2021 Feb;76:108-115.

Planche V, Bouteloup V, Mangin JF, Dubois B, Delrieu J, Pasquier F, Blanc F, Paquet C, Hanon O, Gabelle A, Ceccaldi M, Annweiler C, Krolak-Salmon P, Habert MO, Fischer C, Chupin M, Béjot Y, Godefroy O, Wallon D, Sauvée M, Bourdel-Marchasson I, Jalenques I, Tison F, Chêne G, Dufouil C; and the MEMENTO Study group. Clinical relevance of brain atrophy subtypes categorization in memory clinics. Alzheimers Dement. 2021 ; 17:641-652.

Didic M, Aglieri V, Tramoni-Nègre E, Ronat L, Le Ber I, Ceccaldi M, Belin P, Felician O. Progressive phonagnosia in a telephone operator carrying a C9orf72 expansion. Cortex. 2020 Nov;132:92-98.

Bertoux M, Cassagnaud P, Lebouvier T, Lebert F, Sarazin M, Le Ber I, Dubois B; NeuroCEB Brain Bank, Auriacombe S, Hannequin D, Wallon D, Ceccaldi M, Maurage CA, Deramecourt V, Pasquier F. Does amnesia specifically predict Alzheimer's pathology? A neuropathological study. Neurobiol Aging. 2020 Nov;95:123-130.

Vonk JMJ, Bouteloup V, Mangin JF, Dubois B, Blanc F, Gabelle A, Ceccaldi M, Annweiler C, Krolak-Salmon P, Belin C, Rivasseau-Jonveaux T, Julian A, Sellal F, Magnin E, Chupin M, Habert MO, Chêne G, Dufouil C; MEMENTO cohort Study Group. Semantic loss marks early Alzheimer's disease-related neurodegeneration in older adults without dementia. Alzheimers Dement (Amst). 2020 Aug 5;12(1):e12066.

Benvenutto A, Guedj E, Felician O, Eusebio A, Azulay JP, Ceccaldi M, Koric L. Clinical Phenotypes in Corticobasal Syndrome with or without Amyloidosis Biomarkers. J Alzheimers Dis. 2020;74(1):331-343.

Arbabyazd LM, Lombardo D, Blin O, Didic M, Battaglia D, Jirsa V. Dynamic Functional Connectivity as a complex random walk: Definitions and the dFCwalk toolbox. MethodsX. 2020 Dec 1;7:101168. doi: 10.1016/j.mex.2020.101168. eCollection 2020.

Joubert S, Gardy L, Didic M, Rouleau I, Barbeau EJ. A Meta-Analysis of Semantic Memory in Mild Cognitive Impairment. Neuropsychol Rev. 2020 Aug 19. doi: 10.1007/s11065-020-09453-5. Online ahead of print.

Lombardo D, Cassé-Perrot C, Ranjeva JP, Le Troter A, Guye M, Wirsich J, Payoux P, Bartrés-Faz D, Bordet R, Richardson JC, Felician O, Jirsa V, Blin O, Didic M, Battaglia D. Modular slowing of resting-state dynamic functional connectivity as a marker of cognitive dysfunction induced by sleep deprivation. Neuroimage. 2020 Nov 15;222:117155.

Quattrini G, Pievani M, Jovicich J, Aiello M, Bargalló N, Barkhof F, Bartres-Faz D, Beltramello A, Pizzini FB, Blin O, Bordet R, Caulo M, Constantinides M, Didic M, Drevelegas A, Ferretti A, Fiedler U, Floridi P, Gros-Dagnac H, Hensch T, Hoffmann KT, Kuijer JP, Lopes R, Marra C, Müller BW, Nobili F, Parnetti L, Payoux P, Picco A, Ranjeva JP, Roccatagliata L, Rossini PM, Salvatore M, Schonknecht P, Schott BH, Sein J, Soricelli A, Tarducci R, Tsolaki M, Visser PJ, Wiltfang J, Richardson JC, Frisoni GB, Marizzoni M; PharmaCog Consortium. CSF cutoffs for MCI due to AD depend on APOEε4 carrier status. Neuroimage. 2020 Sep;218:116932.

Marizzoni M, Ferrari C, Babiloni C, Albani D, Barkhof F, Cavaliere L, Didic M, Forloni G, Fusco F, Galluzzi S, Hensch T, Jovicich J, Marra C, Molinuevo JL, Nobili F, Parnetti L, Payoux P, Ranjeva JP, Ribaldi F, Rolandi E, Rossini PM, Salvatore M, Soricelli A, Tsolaki M, Visser PJ, Wiltfang J, Richardson JC, Bordet R, Blin O, Frisoni GB. Amygdalar nuclei and hippocampal subfields on MRI: Test-retest reliability of automated volumetry across different MRI sites and vendors. Neurobiol Aging. 2020 May;89:55-62.

Landelle C, Sein J, Anton JL, Nazarian B, Felician O, Kavounoudias A. The aging brain: A set of functional MRI data acquired at rest and during exposure to tactile or muscle proprioceptive stimulation in healthy young and older volunteers. Data Brief. 2020 Jun 27;31:105939.

Landelle C, Anton JL, Nazarian B, Sein J, Gharbi A, Felician O, Kavounoudias A. Functional brain changes in the elderly for the perception of hand movements: A greater impairment occurs in proprioception than touch. Neuroimage. 2020 Oct 15;220:117056.

Lambert I, Tramoni-Negre E, Lagarde S, Roehri N, Giusiano B, Trebuchon-Da Fonseca A, Carron R, Benar CG, Felician O, Bartolomei F. Hippocampal Interictal Spikes during Sleep Impact Long-Term Memory Consolidation. Ann Neurol. 2020 Jun;87(6):976-987.

Chincarini A, Peira E, Morbelli S, Pardini M, Bauckneht M, Arbizu J, Castelo-Branco M, Büsing KA, de Mendonça A, Didic M, Dottorini M, Engelborghs S, Ferrarese C, Frisoni GB, Garibotto V, Guedj E, Hausner L, Hugon J, Verhaeghe J, Mecocci P, Musarra M, Queneau M, Riverol M, Santana I, Guerra UP, Nobili F. Semi-quantification and grading of amyloid PET: A project of the European Alzheimer's Disease Consortium (EADC). Neuroimage Clin. 2019;23:101846.

Marizzoni M, Ferrari C, Macis A, Jovicich J, Albani D, Babiloni C, Cavaliere L, Didic M, Forloni G, Galluzzi S, Hoffmann KT, Molinuevo JL, Nobili F, Parnetti L, Payoux P, Pizzini F, Rossini PM, Salvatore M, Schönknecht P, Soricelli A, Del Percio C, Hensch T, Hegerl U, Tsolaki M, Visser PJ, Wiltfang J, Richardson JC, Bordet R, Blin O, Frisoni GB; PharmaCog Consortium. Biomarker Matrix to Track Short Term Disease Progression in Amnestic Mild Cognitive Impairment Patients with Prodromal Alzheimer's Disease. J Alzheimers Dis. 2019;69(1):49-58.

Brugnolo A, De Carli F, Pagani M, Morbelli S, Jonsson C, Chincarini A, Frisoni GB, Galluzzi S, Perneczky R, Drzezga A, van Berckel BNM, Ossenkoppele R, Didic M, Guedj E, Arnaldi D, Massa F, Grazzini M, Pardini M, Mecocci P, Dottorini ME, Bauckneht M, Sambuceti G, Nobili F. Head-to-Head Comparison among Semi-Quantification Tools of Brain FDG-PET to Aid the Diagnosis of Prodromal Alzheimer's Disease. J Alzheimers Dis. 2019;68(1):383-394.

Jovicich J, Babiloni C, Ferrari C, Marizzoni M, Moretti DV, Del Percio C, Lizio R, Lopez S, Galluzzi S, Albani D, Cavaliere L, Minati L, Didic M, Fiedler U, Forloni G, Hensch T, Molinuevo JL, Bartrés Faz D, Nobili F, Orlandi D, Parnetti L, Farotti L, Costa C, Payoux P, Rossini PM, Marra C, Schönknecht P, Soricelli A, Noce G, Salvatore M, Tsolaki M, Visser PJ, Richardson JC, Wiltfang J, Bordet R, Blin O, Frisoniand GB; the PharmaCog Consortium. Two-Year Longitudinal Monitoring of Amnestic Mild Cognitive Impairment Patients with Prodromal Alzheimer's Disease Using Topographical Biomarkers Derived from Functional Magnetic Resonance Imaging and Electroencephalographic Activity. J Alzheimers Dis. 2019;69(1):15-35.

Albani D, Marizzoni M, Ferrari C, Fusco F, Boeri L, Raimondi I, Jovicich J, Babiloni C, Soricelli A, Lizio R, Galluzzi S, Cavaliere L, Didic M, Schönknecht P, Molinuevo JL, Nobili F, Parnetti L, Payoux P, Bocchio L, Salvatore M, Rossini PM, Tsolaki M, Visser PJ, Richardson JC, Wiltfang J, Bordet R, Blin O, Forloni G, Frisoni GB; PharmaCog Consortium. Plasma Aβ42 as a Biomarker of Prodromal Alzheimer's Disease Progression in Patients with Amnestic Mild Cognitive Impairment: Evidence from the PharmaCog/E-ADNI Study. J Alzheimers Dis. 2019;69(1):37-48.

Laurens B, Planche V, Cubizolle S, Declerck L, Dupouy S, Formaglio M, Koric L, Seassau M, Tilikete C, Vighetto A, Ceccaldi M, Tison F. A Spatial Decision Eye-Tracking Task in Patients with Prodromal and Mild Alzheimer's Disease. J Alzheimers Dis. 2019 Aug 12;71(2):613-621

Lacour M, Quenez O, Rovelet-Lecrux A, Salomon B, Rousseau S, Richard AC, Quillard-Muraine M, Pasquier F, Rollin-Sillaire A, Martinaud O, Zarea A, de la Sayette V, Boutoleau-Bretonniere C, Etcharry-Bouyx F, Chauviré V, Sarazin M, le Ber I, Epelbaum S, Jonveaux T, Rouaud O, Ceccaldi M, Godefroy O, Formaglio M, Croisile B, Auriacombe S, Magnin E, Sauvée M, Marelli C, Gabelle A, Pariente J, Paquet C, Boland A, Deleuze JF, Campion D, Hannequin D, Nicolas G, Wallon D; collaborators of the CNR-MAJ. Causative Mutations and Genetic Risk Factors in Sporadic Early Onset Alzheimer's Disease Before 51 Years. J Alzheimers Dis. 2019;71(1):227-243.

Tastevin M, Corneille L, Guedj E, Ceccaldi M, Lançon C, Bultingaire V, Richieri R, Koric L. Major depressive disorder masking frontotemporal dementia secondary to C9orf72 mutation: A case report. Rev Neurol (Paris). 2019 Jun;175(6):405-407.

Ceccaldi M. Editorial: Facing up to the complexity of neuro degenerative disorders in order to deal with them more effectively. Curr Opin Neurol. 2019 Apr;32(2):253-254.

Benvenutto A, Giusiano B, Koric L, Gueriot C, Didic M, Felician O, Guye M, Guedj E, Ceccaldi M. Imaging Biomarkers of Neurodegeneration in Alzheimer's Disease: Distinct Contributions of Cortical MRI Atrophy and FDG-PET Hypometabolism. J Alzheimers Dis. 2018;65(4):1147-1157.

Epelbaum S, Bouteloup V, Mangin JF, La Corte V, Migliaccio R, Bertin H, Habert MO, Fischer C, Azouani C, Fillon L, Chupin M, Vellas B, Pasquier F, Dartigues JF, Blanc F, Gabelle A, Ceccaldi M, Krolak-Salmon P, Hugon J, Hanon O, Rouaud O, David R, Chêne G, Dubois B, Dufouil C. Neural correlates of episodic memory in the Memento cohort. Alzheimers Dement (N Y). 2018 May 22;4:224-233.

Roudil J, Deramecourt V, Dufournet B, Dubois B, Ceccaldi M, Duyckaerts C, Pasquier F, Lebouvier T; Brainbank Neuro-CEB Neuropathology Network. Influence of Lewy Pathology on Alzheimer's Disease Phenotype: A Retrospective Clinico-Pathological Study. J Alzheimers Dis. 2018;63(4):1317-1323.

Towards a national strategy on the diagnosis of neurocognitive disorders. A shared approach among the French National College of General Practitioners and specialists of neurocognitive disorders]. Krolak-Salmon P, Letrilliart L, Ceccaldi M, Andrieu S, Guérin O, Dubois B, Brochet B, Vandel P, Jeandel C, Leperre-Desplanques A, Clanet M, Druais PL. Presse Med. 2018 Jan;47(1):75-83.

Touchon J, Rosenbaum J, Aisen P, Andrieu S, Carrillo MC, Ceccaldi M, Dartiques JF, Feldman H, Gabelle A, Isaac M, Fitten LJ, Sperling RA, Vellas B, Tariot P, Weiner M. Editorial: Collaborative Efforts to Prevent Alzheimer's Disease. J Nutr Health Aging. 2017;21(10):1072-1074.

Ceccaldi M, Jonveaux T, Verger A, Krolak-Salmon P, Houzard C, Godefroy O, Shields T, Perrotin A, Gismondi R, Bullich S, Jovalekic A, Raffa N, Pasquier F, Semah F, Dubois B, Habert MO, Wallon D, Chastan M, Payoux P; NEUUS in AD study group, Stephens A, Guedj E. Added value of 18F-florbetaben amyloid PET in the diagnostic workup of most complex patients with dementia in France: A naturalistic study. Alzheimers Dement. 2018 Mar;14(3):293-305.

Cauchoix M, Chow PKY, van Horik JO, Atance CM, Barbeau EJ, Barragan-Jason G, Bize P, Boussard A, Buechel SD, Cabirol A, Cauchard L, Claidière N, Dalesman S, Devaud JM, Didic M, Doligez B, Fagot J, Fichtel C, Henke-von der Malsburg J, Hermer E, Huber L, Huebner F, Kappeler PM, Klein S, Langbein J, Langley EJG, Lea SEG, Lihoreau M, Lovlie H, Matzel LD, Nakagawa S, Nawroth C, Oesterwind S, Sauce B, Smith EA, Sorato E, Tebbich S, Wallis LJ, Whiteside MA, Wilkinson A, Chaine AS, Morand-Ferron J. The repeatability of cognitive performance: a meta-analysis.Philos Trans R Soc Lond B Biol Sci. 2018 Sep 26;373(1756):20170281.

Saracino D, Clot F, Camuzat A, Anquetil V, Hannequin D, Guyant-Maréchal L, Didic M, Guillot-Noël L, Rinaldi D, Latouche M, Forlani S, Ghassab Y, Coppola C, Di Iorio G, David I; French research network on FTD/FTD-ALS, Le Guern E, Brice A, Le Ber I. Novel VCP mutations expand the mutational spectrum of frontotemporal dementia. Neurobiol Aging. 2018 Dec;72:187.e11-187.e14.

Marizzoni M, Ferrari C, Jovicich J, Albani D, Babiloni C, Cavaliere L, Didic M, Forloni G, Galluzzi S, Hoffmann KT, Molinuevo JL, Nobili F, Parnetti L, Payoux P, Ribaldi F, Rossini PM, Schönknecht P, Salvatore M, Soricelli A, Hensch T, Tsolaki M, Visser PJ, Wiltfang J, Richardson JC, Bordet R, Blin O, Frisoni GB; PharmaCog Consortium. Predicting and Tracking Short Term Disease Progression in Amnestic Mild Cognitive Impairment Patients with Prodromal Alzheimer's Disease: Structural Brain Biomarkers. J Alzheimers Dis. 2019;69(1):3-14.

Ceccaldi M, Jonveaux T, Verger A, Krolak-Salmon P, Houzard C, Godefroy O, Shields T, Perrotin A, Gismondi R, Bullich S, Jovalekic A, Raffa N, Pasquier F, Semah F, Dubois B, Habert MO, Wallon D, Chastan M, Payoux P; NEUUS in AD study group, Stephens A, Guedj E. Added value of 18F-florbetaben amyloid PET in the diagnostic workup of most complex patients with dementia in France: A naturalistic study. Alzheimers Dement. 2018 Mar;14(3):293-305

Bergeron D, Gorno-Tempini ML, Rabinovici GD, Santos-Santos MA, Seeley W, Miller BL, Pijnenburg Y, Keulen MA, Groot C, van Berckel BNM, van der Flier WM, Scheltens P, Rohrer JD, Warren JD, Schott JM, Fox NC, Sanchez-Valle R, Grau-Rivera O, Gelpi E, Seelaar H, Papma JM, van Swieten JC, Hodges JR, Leyton CE, Piguet O, Rogalski EJ, Mesulam MM, Koric L, Nora K, Pariente J, Dickerson B, Mackenzie IR, Hsiung GR, Belliard S, Irwin DJ, Wolk DA, Grossman M, Jones M, Harris J, Mann D, Snowden JS, Chrem-Mendez P, Calandri IL, Amengual AA, Miguet-Alfonsi C, Magnin E, Magnani G, Santangelo R, Deramecourt V, Pasquier F, Mattsson N, Nilsson C, Hansson O, Keith J, Masellis M, Black SE, Matías-Guiu JA, Cabrera-Martin MN, Paquet C, Dumurgier J, Teichmann M, Sarazin M, Bottlaender M, Dubois B, Rowe CC, Villemagne VL, Vandenberghe R, Granadillo E, Teng E, Mendez M, Meyer PT, Frings L, Lleó A, Blesa R, Fortea J, Seo SW, Diehl-Schmid J, Grimmer T, Frederiksen KS, Sánchez-Juan P, Chételat G, Jansen W, Bouchard RW, Laforce RJ, Visser PJ, Ossenkoppele R. Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia. Ann Neurol. 2018 Nov;84(5):729-740.

Holden JG, Cosnard A, Laurens B, Asselineau J, Biotti D, Cubizolle S, Dupouy S, Formaglio M, Koric L, Seassau M, Tilikete C, Vighetto A, Tison F. Prodromal Alzheimer's Disease Demonstrates Increased Errors at a Simple and Automated Anti-Saccade Task. J Alzheimers Dis. 2018;65(4):1209-1223.

Chancel M, Landelle C, Blanchard C, Felician O, Guerraz M, Kavounoudias A. Hand movement illusions show changes in sensory reliance and preservation of multisensory integration with age for kinaesthesia. Neuropsychologia. 2018 Oct;119:45-58.

Brissart H, Planton M, Bilger M, Bulteau C, Forthoffer N, Guinet V, Hennion S, Kleitz C, Laguitton V, Mirabel H, Mosca C, Pécheux N, Pradier S, Samson S, Tramoni E, Voltzenlogel V, Denos M, Boutin M. French neuropsychological procedure consensus in epilepsy surgery.  Epilepsy Behav. 2019 Nov;100(Pt A):106522.

Larzabal C, Tramoni E, Muratot S, Thorpe SJ, Barbeau EJ. Extremely long-term memory and familiarity after 12 years. Cognition. 2018 Jan;170:254-262.

Crutch SJ, Schott JM, Rabinovici GD, Murray M, Snowden JS, van der Flier WM, Dickerson BC, Vandenberghe R,  Ahmed S, Bak TH, Boeve BF, Butler C, Cappa SF, Ceccaldi M, de Souza LC, Dubois B, Felician O, Galasko D, Graff-Radford J, Graff-Radford NR, Hof PR, Krolak-Salmon P, Lehmann M, Magnin E, Mendez MF, Nestor PJ, Onyike CU, Pelak VS, Pijnenburg Y, Primativo S, Rossor MN, Ryan NS, Scheltens P, Shakespeare TJ, González AS, Tang-Wai DF, Yong KX, Carrillo M, Fox NC on behalf of the Alzheimer’s Association ISTAART Atypical Alzheimer’s Disease and Associated Syndromes Professional Interest Area. Consensus classification of posterior cortical atrophy. Alzheimer’s and Dementia, 2017; 13(8): 870-884.

Tramoni E, Lambert I, Bartolomei F, Felician O. Long-term memory deficits in temporal lobe epilepsy. Revue Neurologique, 2017; 173: 490-7.

Verger A, Roman S, Chaudat RM, Felician O, Ceccaldi M, Didic M, Guedj E. Changes of metabolism and functional connectivity in late-onset deafness: Evidence from cerebral 18F-FDG-PET. Hearing Research 2017; 353: 8-16.

Aziz AL, Giusiano B, Joubert S, Duprat L, Didic M, Gueriot C, Koric L, Boucraut J, Felician O, Ranjeva JP, Guedj E, Ceccaldi M. Difference in imaging biomarkers of neurodegeneration between early and late-onset amnestic Alzheimer’s disease. Neurobiology of Aging, 2017; 54: 22-30.

Lanoiselée HM, Nicolas G, Wallon D, Rovelet-Lecrux A, Lacour M, Rousseau S, Richard AC, Pasquier F, Rollin-Sillaire A, Martinaud O, Quillard-Muraine M, de la Sayette V, Boutoleau-Bretonniere C, Etcharry-Bouyx F, Chauviré V, Sarazin M, le Ber I, Epelbaum S, Jonveaux T, Rouaud O, Ceccaldi M, Felician O, Godefroy O, Formaglio M, Croisile B, Auriacombe S, Chamard L, Vincent JL, Sauvée M, Marelli-Tosi C, Gabelle A, Ozsancak C, Pariente J, Paquet C, Hannequin D, Campion D; collaborators of the CNR-MAJ project. APP, PSEN1, and PSEN2 mutations in early-onset Alzheimer disease: A genetic screening study of familial and sporadic cases. PLoS Medicine 2017 28;14(3):e1002270. doi: 10.

Dufouil C, Dubois B, Vellas B, Pasquier F, Blanc F, Hugon J, Hanon O, Dartigues JF, Harston S, Gabelle A, Ceccaldi M, Beauchet O, Krolak-Salmon P, David R, Rouaud O, Godefroy O, Belin C, Rouch I, Auguste N, Wallon D, Benetos A, Pariente J, Paccalin M, Moreaud O, Hommet C, Sellal F, Boutoleau-Bretonniére C, Jalenques I, Gentric A, Vandel P, Azouani C, Fillon L, Fischer C, Savarieau H, Operto G, Bertin H, Chupin M, Bouteloup V, Habert MO, Mangin JF, Chêne G; MEMENTO cohort Study Group. Cognitive and imaging markers in non-demented subjects attending a memory clinic: study design and baseline findings of the MEMENTO cohort. Alzheimers Res Ther. 2017;9:67.

Costa A, Bak T, Caffarra P, Caltagirone C, Ceccaldi M, Collette F, Crutch S, Della Sala S, Démonet JF, Dubois B, Duzel E, Nestor P, Papageorgiou SG, Salmon E, Sikkes S, Tiraboschi P, van der Flier WM, Visser PJ, Cappa SF. The need for harmonisation and innovation of neuropsychological assessment in neurodegenerative dementias in Europe: consensus document of the Joint Program for Neurodegenerative Diseases Working Group. Alzheimers Res Ther. 2017;9:27.

Bos I, Vos SJ, Frölich L, Kornhuber J, Wiltfang J, Maier W, Peters O, Rüther E, Engelborghs S, Niemantsverdriet E, De Roeck EE, Tsolaki M, Freund-Levi Y, Johannsen P, Vandenberghe R, Lleó A, Alcolea D, Frisoni GB, Galluzzi S, Nobili F, Morbelli S, Drzezga A, Didic M, van Berckel BN, Salmon E, Bastin C, Dauby S, Santana I, Baldeiras I, de Mendonça A, Silva D, Wallin A, Nordlund A, Coloma PM, Wientzek A, Alexander M, Novak GP, Gordon MF; Alzheimer's Disease Neuroimaging Initiative, Wallin ÅK, Hampel H, Soininen H, Herukka SK, Scheltens P, Verhey FR, Visser PJ. The frequency and influence of dementia risk factors in prodromal Alzheimer's disease. Neurobiol Aging. 2017;56:33-40.

Nathan PJ, Lim YY, Abbott R, Galluzzi S, Marizzoni M, Babiloni C, Albani D, Bartres-Faz D, Didic M, Farotti L, Parnetti L, Salvadori N, Müller BW, Forloni G, Girtler N, Hensch T, Jovicich J, Leeuwis A, Marra C, Molinuevo JL, Nobili F, Pariente J, Payoux P, Ranjeva JP, Rolandi E, Rossini PM, Schönknecht P, Soricelli A, Tsolaki M, Visser PJ, Wiltfang J, Richardson JC, Bordet R, Blin O, Frisoni GB; PharmaCog Consortium. Association between CSF biomarkers, hippocampal volume and cognitive function in patients with amnestic mild cognitive impairment (MCI). Neurobiol Aging. 2017;53:1-10.

Albi A, Pasternak O, Minati L, Marizzoni M, Bartrés-Faz D, Bargalló N, Bosch B, Rossini PM, Marra C, Müller B, Fiedler U, Wiltfang J, Roccatagliata L, Picco A, Nobili FM, Blin O, Sein J, Ranjeva JP, Didic M, Bombois S, Lopes R, Bordet R, Gros-Dagnac H, Payoux P, Zoccatelli G, Alessandrini F, Beltramello A, Ferretti A, Caulo M, Aiello M, Cavaliere C, Soricelli A, Parnetti L, Tarducci R, Floridi P, Tsolaki M, Constantinidis M, Drevelegas A, Frisoni G, Jovicich J; PharmaCog Consortium. Free water elimination improves test-retest reproducibility of diffusion tensor imaging indices in the brain: A longitudinal multisite study of healthy elderly subjects. Hum Brain Mapp. 2017;38:12-26.

Besson G, Barragan-Jason G, Thorpe SJ, Fabre-Thorpe M, Puma S, Ceccaldi M, Barbeau EJ. From face processing to face recognition: Comparing three different processing levels. Cognition. 2017;158:33-43.

Recherches :

Essais cliniques en cours :

• Addition
• ALNTTRO2-006
• Baxalta
• Dysferlin
• Dyvine
• Expret
• Helipad
• Igos
• Mirocals
• Mycopid
• NeoGAA comete
• Neuroinflammation
• Nutrals
• Obsamyl
• Pulse

Essais à venir :

• Eidos
• Helios ALNTTRSC02
• POM-003 Amicus
• Mom-M281-004
• Syneos ARGX-113 Myasthenia Gravis
• 161505-extension baxalta PIDC
• Dermatomyositis igoPro20_3007
• Biogen 233AS301
• Fair ALS
• Pharm-Olam
• Rock als

Publications :

• Adams D, Gonzalez-Duarte A, O'Riordan WD, Yang CC, Ueda M, Kristen AV, Tournev I, Schmidt HH, Coelho T, Berk JL, Lin KP, Vita G, Attarian S, Planté-Bordeneuve V, Mezei MM, Campistol JM, Buades J, Brannagan TH 3rd, Kim BJ, Oh J, Parman Y, Sekijima Y, Hawkins PN, Solomon SD, Polydefkis M, Dyck PJ, Gandhi PJ, Goyal S, Chen J, Strahs AL, Nochur SV, Sweetser MT, Garg PP, Vaishnaw AK, Gollob JA, Suhr OB. Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis. N Engl J Med. 2018 Jul 5;379(1):11-21. doi: 10.1056/NEJMoa1716153. PubMed PMID: 29972753.

• Bas J, Delmont E, Fatehi F, Salort-Campana E, Verschueren A, Pouget J, Lefebvre MN, Grapperon AM, Attarian S. Motor unit number index correlates with disability in Charcot-Marie-Tooth disease. Clin Neurophysiol. 2018 Jul;129(7):1390-1396. doi: 10.1016/j.clinph.2018.04.359. Epub 2018 Apr 16. PubMed PMID: 29729594.

• van Schaik IN, Mielke O; PATH study group. Intravenous versus subcutaneous immunoglobulin - Authors' reply. Lancet Neurol. 2018 May;17(5):393-394. doi: 10.1016/S1474-4422(18)30109-1. PubMed PMID: 29656738.

• Attarian SJ, Leibel SL, Yang P, Alfano DN, Hackett BP, Cole FS, Hamvas A. Mutations in the thyroid transcription factor gene NKX2-1 result in decreased expression of SFTPB and SFTPC. Pediatr Res. 2018 Apr 11. doi: 10.1038/pr.2018.30. [Epub ahead of print] PubMed PMID: 29538355.

• Ben Lassoued A, Fromonot J, Marlinge M, Basset N, Chefrour M, Vairo D, Couillaud J, Lopez L, Cuisset T, Boucraut J, Delmont E, Attarian S, Guieu R. Corrigendum to "A case of false positive cardiac troponin I in CANOMAD syndrome" [Int. J. Cardiol. 222 (2016) 359-360]. Int J Cardiol. 2018 May 15;259:234. doi: 10.1016/j.ijcard.2018.02.017. Epub  2018 Feb 27. PubMed PMID: 29499853.

• Duchesne M, Danigo A, Richard L, Vallat JM, Attarian S, Gonnaud PM, Lacour A, Péréon Y, Stojkovic T, Nave KA, Bertrand V, Nabirotchkin S, Cohen D, Demiot C, Magy L. Skin Biopsy Findings in Patients With CMT1A: Baseline Data From the CLN-PXT3003-01 Study Provide New Insights Into the Pathophysiology of the Disorder. J Neuropathol Exp Neurol. 2018 Apr 1;77(4):274-281. doi: 10.1093/jnen/nly001. PubMed PMID: 29408953.

• Van den Bergh PYK, Piéret F, Woodard JL, Attarian S, Grapperon AM, Nicolas G, Brisset M, Cassereau J, Rajabally YA, Van Parijs V, Verougstraete D, Jacquerye P, Raymackers JM, Redant C, Michel C, Delmont E; University of Louvain GBS Electrodiagnosis Study Group. Guillain-BarrÉ syndrome subtype diagnosis: A prospective multicentric  European study. Muscle Nerve. 2018 Jan 5. doi: 10.1002/mus.26056. [Epub ahead of print] PubMed PMID: 29315669.

• Attarian S, Yu C, Anderson KE, Friedman EW. Effects of hemin and hemodialysis in a patient with acute intermittent porphyria and renal failure. Blood Adv. 2017 Jun 5;1(14):915-917. doi: 10.1182/bloodadvances.2017005660. eCollection 2017 Jun 13. PubMed PMID: 29296735; PubMed Central PMCID: PMC5737596.

• Rajabally YA, Attarian S. Chronic inflammatory demyelinating polyneuropathy and malignancy: A systematic review. Muscle Nerve. 2018 Jun;57(6):875-883. doi: 10.1002/mus.26028. Epub 2017 Dec 20. Review. PubMed PMID: 29194677.

• Sevy A, Grapperon AM, Salort Campana E, Delmont E, Attarian S. Detection of proximal conduction blocks using a triple stimulation technique improves the early diagnosis of Guillain-Barré syndrome. Clin Neurophysiol. 2018 Jan;129(1):127-132. doi: 10.1016/j.clinph.2017.10.035. Epub 2017 Nov 11. PubMed PMID: 29182914.

• Attarian S, Reed L, Singh S, Shestopalov A, Singh AP, Budhathoki A, Abi-Aad S, Shah UA, Kim S, Bachiashvili K, Elrafei T, Li W, Yee C, Friedman EW. Visualization of the bone marrow biopsy needle track. Am J Hematol. 2018 Mar;93(3):E60-E61. doi: 10.1002/ajh.24985. Epub 2017 Dec 6. PubMed PMID: 29168229.

• Ibrahim J, Grapperon AM, Manfredonia F, van den Bergh PY, Attarian S, Rajabally YA. Serial electrophysiology in Guillain-Barré syndrome: A retrospective cohort and case-by-case multicentre analysis. Acta Neurol Scand. 2018 Mar;137(3):335-340. doi: 10.1111/ane.12872. Epub 2017 Nov 21. PubMed PMID: 29164611.

• Martinez-Martinez L, Lleixà MC, Boera-Carnicero G, Cortese A, Devaux J, Siles A, Rajabally Y, Martinez-Piñeiro A, Carvajal A, Pardo J, Delmont E, Attarian S, Diaz-Manera J, Callegari I, Marchioni E, Franciotta D, Benedetti L, Lauria G, de la Calle Martin O, Juárez C, Illa I, Querol L. Anti-NF155 chronic inflammatory demyelinating polyradiculoneuropathy strongly associates to HLA-DRB15. J Neuroinflammation. 2017 Nov 16;14(1):224. doi: 10.1186/s12974-017-0996-1. PubMed PMID: 29145880; PubMed Central PMCID: PMC5691853.

• Marion S, Béhin A, Attarian S. [GNE myopathy: proven failure of sialic acid supplementation… what's next?]. Med Sci (Paris). 2017 Nov;33 Hors série n°1:55-56. doi: 10.1051/medsci/201733s111. Epub 2017 Nov 15. French. PubMed PMID: 29139388.

• van Schaik IN, Bril V, van Geloven N, Hartung HP, Lewis RA, Sobue G, Lawo JP, Praus M, Mielke O, Durn BL, Cornblath DR, Merkies ISJ; PATH study group. Subcutaneous immunoglobulin for maintenance treatment in chronic inflammatory demyelinating polyneuropathy (PATH): a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet Neurol. 2018 Jan;17(1):35-46. doi: 10.1016/S1474-4422(17)30378-2. Epub 2017 Nov 6. Erratum in: Lancet Neurol. 2018 Jan;17 (1):26. Lancet Neurol. 2018 Aug;17(8):661. PubMed PMID: 29122523.

• Rasoanandrianina H, Grapperon AM, Taso M, Girard OM, Duhamel G, Guye M, Ranjeva JP, Attarian S, Verschueren A, Callot V. Region-specific impairment of the cervical spinal cord (SC) in amyotrophic lateral sclerosis: A preliminary study using SC templates and quantitative MRI (diffusion tensor imaging/inhomogeneous magnetization transfer). NMR Biomed. 2017 Dec;30(12). doi: 10.1002/nbm.3801. Epub 2017 Sep 19. PubMed PMID: 28926131.

• Rajabally YA, Delmont E, Hiew FL, Aubé-Nathier AC, Grapperon AM, Cassereau J, Attarian S. Prevalence, correlates and impact of pain and cramps in anti-MAG neuropathy: a multicentre European study. Eur J Neurol. 2018 Jan;25(1):135-141. doi: 10.1111/ene.13459. Epub 2017 Oct 19. PubMed PMID: 28906575.

• Fatehi F, Salort-Campana E, Le Troter A, Lareau-Trudel E, Bydder M, Fouré A, Guye M, Bendahan D, Attarian S. Long-term follow-up of MRI changes in thigh muscles of patients with Facioscapulohumeral dystrophy: A quantitative study. PLoS One. 2017 Aug 25;12(8):e0183825. doi: 10.1371/journal.pone.0183825. eCollection 2017. PubMed PMID: 28841698; PubMed Central PMCID: PMC5571945. 

• van Eijk JJJ, Dalton HR, Ripellino P, Madden RG, Jones C, Fritz M, Gobbi C, Melli G, Pasi E, Herrod J, Lissmann RF, Ashraf HH, Abdelrahim M, Masri OABAL, Fraga M, Benninger D, Kuntzer T, Aubert V, Sahli R, Moradpour D, Blasco-Perrin H, Attarian S, Gérolami R, Colson P, Giordani MT, Hartl J, Pischke S, Lin NX, Mclean BN, Bendall RP, Panning M, Peron JM, Kamar N, Izopet J, Jacobs BC, van Alfen N, van Engelen BGM. Clinical phenotype and outcome of hepatitis E virus-associated neuralgic amyotrophy. Neurology. 2017 Aug 29;89(9):909-917. doi: 10.1212/WNL.0000000000004297. Epub 2017 Aug 2. PubMed PMID: 28768846.

• Attarian S, Sharma J, Kaubisch A, Zonszein J, Haigentz M Jr. Multiple Endocrine and Neoplastic Diseases After Unsuccessful Treatment of Hepatitis C With Interferon and Ribavirin. Am J Med Sci. 2017 Jul;354(1):66. doi: 10.1016/j.amjms.2016.10.001. Epub 2016 Oct 18. PubMed PMID: 28755736.

• Nguyen K, Puppo F, Roche S, Gaillard MC, Chaix C, Lagarde A, Pierret M, Vovan C, Olschwang S, Salort-Campana E, Attarian S, Bartoli M, Bernard R, Magdinier F, Levy N. Molecular combing reveals complex 4q35 rearrangements in Facioscapulohumeral dystrophy. Hum Mutat. 2017 Oct;38(10):1432-1441. doi: 10.1002/humu.23304. Epub 2017 Aug 6. PubMed PMID: 28744936.

• Mul K, Kinoshita J, Dawkins H, van Engelen B, Tupler R; FSHD Consortium. 225th ENMC international workshop:: A global FSHD registry framework, 18-20 November 2016, Heemskerk, The Netherlands. Neuromuscul Disord. 2017 Aug;27(8):782-790. doi: 10.1016/j.nmd.2017.04.004. Epub 2017 Apr 12. PubMed PMID: 28625604.

• Franques J, Sahuc P, Dussol B, Penaranda G, Swiader L, Froissart R, Attarian S, Stavris C, Chiche L, Pouget J. Peripheral nerve involvement in Fabry's disease: Which investigations? A case series and review of the literature. Rev Neurol (Paris). 2017 Dec;173(10):650-657. doi: 10.1016/j.neurol.2017.05.007. Epub 2017 Jun 1. Review. PubMed PMID: 28579207.

• Delmont E, Manso C, Querol L, Cortese A, Berardinelli A, Lozza A, Belghazi M, Malissart P, Labauge P, Taieb G, Yuki N, Illa I, Attarian S, Devaux JJ. Autoantibodies to nodal isoforms of neurofascin in chronic inflammatory demyelinating polyneuropathy. Brain. 2017 Jul 1;140(7):1851-1858. doi: 10.1093/brain/awx124. PubMed PMID: 28575198.

• Fatehi F, Delmont E, Grapperon AM, Salort-Campana E, Sévy A, Verschueren A, Boucraut J, Attarian S. Motor unit number index (MUNIX) in patients with anti-MAG neuropathy. Clin Neurophysiol. 2017 Jul;128(7):1264-1269. doi: 10.1016/j.clinph.2017.04.022. Epub 2017 May 9. PubMed PMID: 28545015. 

• Gazzola S, Delmont E, Franques J, Boucraut J, Salort-Campana E, Verschueren A, Sagui E, Hubert AM, Pouget J, Attarian S. Predictive factors of efficacy of rituximab in patients with anti-MAG neuropathy. J Neurol Sci. 2017 Jun 15;377:144-148. doi: 10.1016/j.jns.2017.04.015. Epub 2017 Apr 12. PubMed PMID: 28477685.

• Grapperon AM, Attarian S. Disorders of motor neurons manifested by hyperactivity. Rev Neurol (Paris). 2017 May;173(5):345-351. doi: 10.1016/j.neurol.2017.04.002. Epub 2017 Apr 28. Review. PubMed PMID: 28457490.

• Jacobs BC, van den Berg B, Verboon C, Chavada G, Cornblath DR, Gorson KC, Harbo T, Hartung HP, Hughes RAC, Kusunoki S, van Doorn PA, Willison HJ; IGOS Consortium. International Guillain-Barré Syndrome Outcome Study: protocol of a prospective observational cohort study on clinical and biological predictors of disease course and outcome in Guillain-Barré syndrome. J Peripher Nerv Syst. 2017 Jun;22(2):68-76. doi: 10.1111/jns.12209. PubMed PMID: 28406555.

• Leporq B, Le Troter A, Le Fur Y, Salort-Campana E, Guye M, Beuf O, Attarian S, Bendahan D. Combined quantification of fatty infiltration, T (1)-relaxation times and T (2)*-relaxation times in normal-appearing skeletal muscle of controls and dystrophic patients. MAGMA. 2017 Aug;30(4):407-415. doi: 10.1007/s10334-017-0616-1. Epub 2017 Mar 22. PubMed PMID: 28332039.

• Attarian S, Karami A, Ayatolahi F. Combination Therapy of Infections Caused by Injection of Paint Using Medical Laser. World J Plast Surg. 2017 Jan;6(1):120-122. PubMed PMID: 28289626; PubMed Central PMCID: PMC5339622.

• Cerino M, Gorokhova S, Laforet P, Ben Yaou R, Salort-Campana E, Pouget J, Attarian S, Eymard B, Deleuze JF, Boland A, Behin A, Stojkovic T, Bonne G, Levy N, Bartoli M, Krahn M. Genetic Characterization of a French Cohort of GNE-mutation negative inclusion body myopathy patients with exome sequencing. Muscle Nerve. 2017 Nov;56(5):993-997. doi: 10.1002/mus.25638. Epub 2017 Apr 7. PubMed PMID: 28256728.

• Grimaldi S, Duprat L, Grapperon AM, Verschueren A, Delmont E, Attarian S. Global motor unit number index sum score for assessing the loss of lower motor neurons in amyotrophic lateral sclerosis. Muscle Nerve. 2017 Aug;56(2):202-206. doi: 10.1002/mus.25595. Epub 2017 Apr 1. PubMed PMID: 28164325.

• Gesquière-Dando A, Delmont E, Launay M, Boucraut J, Attarian S. Are electrophysiological features related to disability in patients with anti-MAG neuropathy? Neurophysiol Clin. 2017 Feb;47(1):75-81. doi: 10.1016/j.neucli.2017.01.002. Epub 2017 Feb 1. PubMed PMID: 28161089.

• Wang W, Guedj M, Bertrand V, Foucquier J, Jouve E, Commenges D, Proust-Lima C, Murphy NP, Blin O, Magy L, Cohen D, Attarian S. A Rasch Analysis of the Charcot-Marie-Tooth Neuropathy Score (CMTNS) in a Cohort of Charcot-Marie-Tooth Type 1A Patients. PLoS One. 2017 Jan 17;12(1):e0169878. doi: 10.1371/journal.pone.0169878. eCollection 2017. PubMed PMID: 28095456; PubMed Central PMCID: PMC5240958.

• Duclos Y, Grapperon AM, Jouve E, Truillet R, Zemmour C, Verschueren A, Pouget J, Attarian S. Motor-evoked potential gain is a helpful test for the detection of corticospinal tract dysfunction in amyotrophic lateral sclerosis. Clin Neurophysiol. 2017 Feb;128(2):357-364. doi: 10.1016/j.clinph.2016.12.015. Epub 2016 Dec 23. PubMed PMID: 28068522.

• Philibert M, Grapperon AM, Delmont E, Attarian S. Monitoring the short-term effect of intravenous immunoglobulins in multifocal motor neuropathy using motor unit number index. Clin Neurophysiol. 2017 Jan;128(1):235-240. doi: 10.1016/j.clinph.2016.11.012. Epub 2016 Dec 1. PubMed PMID: 27988478.

• Delmont E, Hiew FL, Cassereau J, Aubé-Nathier AC, Grapperon AM, Attarian S, Rajabally YA. Determinants of health-related quality of life in anti-MAG neuropathy: a cross-sectional multicentre European study. J Peripher Nerv Syst. 2017 Mar;22(1):27-33. doi: 10.1111/jns.12197. PubMed PMID: 27868289.

• Fatehi F, Salort-Campana E, Le Troter A, Bendahan D, Attarian S. Muscle MRI of facioscapulohumeral dystrophy (FSHD): A growing demand and a promising approach. Rev Neurol (Paris). 2016 Oct;172(10):566-571. doi: 10.1016/j.neurol.2016.08.002. Epub 2016 Sep 20. Review. PubMed PMID: 27663058.

• Gaillard MC, Puppo F, Roche S, Dion C, Campana ES, Mariot V, Chaix C, Vovan C, Mazaleyrat K, Tasmadjian A, Bernard R, Dumonceaux J, Attarian S, Lévy N, Nguyen K, Magdinier F, Bartoli M. Segregation between SMCHD1 mutation, D4Z4 hypomethylation and Facio-Scapulo-Humeral Dystrophy: a case report. BMC Med Genet. 2016 Sep 15;17(1):66. doi: 10.1186/s12881-016-0328-9. PubMed PMID: 27634379; PubMed Central PMCID: PMC5025538.

• Bou Ali H, Salort-Campana E, Grapperon AM, Gallard J, Franques J, Sevy A, Delmont E, Verschueren A, Pouget J, Attarian S. New strategy for improving the diagnostic sensitivity of repetitive nerve stimulation in myasthenia gravis. Muscle Nerve. 2017 Apr;55(4):532-538. doi: 10.1002/mus.25374. Epub 2017 Jan 3. PubMed PMID: 27511866.

• Ben Lassoued A, Fromonot J, Marlinge M, Basset N, Chefrour M, Vairo D, Couillaud J, Lopez L, Cuisset T, Boucraut J, Delmont E, Attarian S, Guieu R. A case of false positive cardiac troponin I in CANOMAD syndrome. Int J Cardiol. 2016 Nov 1;222:359-360. doi: 10.1016/j.ijcard.2016.07.297. Epub 2016 Aug 2. Erratum in: Int J Cardiol. 2018 Feb 27;:. PubMed PMID: 27500764.

• Sicello M, Sevy A, Borentain P, Gérolami R, Attarian S, Colson P. Evolution of hepatitis E virus-associated meningo-polyradiculoneuropathy on ribavirin. Int J Antimicrob Agents. 2016 Sep;48(3):343-5. doi: 10.1016/j.ijantimicag.2016.06.004. Epub 2016 Jul 8. PubMed PMID: 27470489.

• Attarian S, Vallat JM, Magy L, Funalot B, Gonnaud PM, Lacour A, Péréon Y, Dubourg O, Pouget J, Micallef J, Franques J, Lefebvre MN, Ghorab K, Al-Moussawi M, Tiffreau V, Preudhomme M, Magot A, Leclair-Visonneau L, Stojkovic T, Bossi L, Lehert P, Gilbert W, Bertrand V, Mandel J, Milet A, Hajj R, Boudiaf L, Scart-Grès C, Nabirotchkin S, Guedj M, Chumakov I, Cohen D. Erratum to: An exploratory randomised double-blind and placebo-controlled phase 2 study of a combination of baclofen, naltrexone and sorbitol (PXT3003) in patients with Charcot-Marie-Tooth disease type 1A. Orphanet J Rare Dis. 2016 Jul 7;11(1):92. PubMed PMID: 27387831; PubMed Central PMCID: PMC4937550.

• Runnqvist E, Bonnard M, Gauvin HS, Attarian S, Trébuchon A, Hartsuiker RJ, Alario FX. Internal modeling of upcoming speech: A causal role of the right posterior cerebellum in non-motor aspects of language production. Cortex. 2016 Aug;81:203-14. doi: 10.1016/j.cortex.2016.05.008. Epub 2016 May 21. PubMed PMID: 27249802.

• Béhin A, Acquaviva-Bourdain C, Souvannanorath S, Streichenberger N, Attarian  S, Bassez G, Brivet M, Fouilhoux A, Labarre-Villa A, Laquerrière A, Pérard L, Kaminsky P, Pouget J, Rigal O, Vanhulle C, Eymard B, Vianey-Saban C, Laforêt P. Multiple acyl-CoA dehydrogenase deficiency (MADD) as a cause of late-onset treatable metabolic disease. Rev Neurol (Paris). 2016 Mar;172(3):231-41. doi: 10.1016/j.neurol.2015.11.008. Epub 2016 Mar 30. PubMed PMID: 27038534.

• Rajabally YA, Adams D, Latour P, Attarian S. Hereditary and inflammatory neuropathies: a review of reported associations, mimics and misdiagnoses. J Neurol Neurosurg Psychiatry. 2016 Oct;87(10):1051-60. doi: 10.1136/jnnp-2015-310835. Epub 2016 Mar 23. Review. PubMed PMID: 27010614.

• Delmont E, Benvenutto A, Grimaldi S, Duprat L, Philibert M, Pouget J, Grapperon AM, Salort-Campana E, Sévy A, Verschueren A, Attarian S. Motor unit number index (MUNIX): Is it relevant in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP)? Clin Neurophysiol. 2016 Mar;127(3):1891-4. doi: 10.1016/j.clinph.2015.12.002. Epub 2015 Dec 12. PubMed PMID: 26750580.

• Fatehi F, Nafissi S, Urtizberea JA, Blanck-Labelle V, Lévy N, Krahn M, Dbouk MB, Attarian S. Dysferlinopathy in Iran: Clinical and genetic report. J Neurol Sci. 2015 Dec 15;359(1-2):256-9. doi: 10.1016/j.jns.2015.11.009. Epub 2015 Nov 11. PubMed PMID: 26671124.

• Mariani LL, Lozeron P, Théaudin M, Mincheva Z, Signate A, Ducot B, Algalarrondo V, Denier C, Adam C, Nicolas G, Samuel D, Slama MS, Lacroix C, Misrahi M, Adams D; French Familial Amyloid Polyneuropathies Network (CORNAMYL) Study Group. Genotype-phenotype correlation and course of transthyretin familial amyloid polyneuropathies in France. Ann Neurol. 2015 Dec;78(6):901-16. doi: 10.1002/ana.24519. Epub 2015 Oct 7. PubMed PMID: 26369527; PubMed Central PMCID: PMC4738459.

• Béhin A, Salort-Campana E, Wahbi K, Richard P, Carlier RY, Carlier P, Laforêt P, Stojkovic T, Maisonobe T, Verschueren A, Franques J, Attarian S, Maues de Paula A, Figarella-Branger D, Bécane HM, Nelson I, Duboc D, Bonne G, Vicart P, Udd B, Romero N, Pouget J, Eymard B. Myofibrillar myopathies: State of the art, present and future challenges. Rev Neurol (Paris). 2015 Oct;171(10):715-29. doi: 10.1016/j.neurol.2015.06.002. Epub 2015 Sep 3. Review. PubMed PMID: 26342832.

• Verschueren A, Gallard J, Boucraut J, Honnorat J, Pouget J, Attarian S. Paraneoplastic subacute lower motor neuron syndrome associated with solid cancer. J Neurol Sci. 2015 Nov 15;358(1-2):413-6. doi: 10.1016/j.jns.2015.08.014. Epub 2015 Aug 12. PubMed PMID: 26323521.

• Lareau-Trudel E, Le Troter A, Ghattas B, Pouget J, Attarian S, Bendahan D, Salort-Campana E. Muscle Quantitative MR Imaging and Clustering Analysis in Patients with Facioscapulohumeral Muscular Dystrophy Type 1. PLoS One. 2015 Jul 16;10(7):e0132717. doi: 10.1371/journal.pone.0132717. eCollection 2015. PubMed PMID: 26181385; PubMed Central PMCID: PMC4504465.

• Attarian S, Libutti SK, Chuy J. ACTH-Producing Pancreatic Neuroendocrine Tumor Presenting with Severe Hypokalemic Alkalosis: A Case Report. J Gastrointest Cancer. 2016 Jun;47(2):217-20. doi: 10.1007/s12029-015-9740-1. PubMed PMID: 26073616.

• Mandel J, Bertrand V, Lehert P, Attarian S, Magy L, Micallef J, Chumakov I, Scart-Grès C, Guedj M, Cohen D. A meta-analysis of randomized double-blind clinical trials in CMT1A to assess the change from baseline in CMTNS and ONLS scales after one year of treatment. Orphanet J Rare Dis. 2015 Jun 13;10:74. doi: 10.1186/s13023-015-0293-y. PubMed PMID: 26070802; PubMed Central PMCID: PMC4482281.

• Taieb G, Grapperon AM, Duclos Y, Franques J, Labauge P, Renard D, Yuki N, Attarian S. Proximal conduction block in the pharyngeal-cervical-brachial variant of Guillain-Barré syndrome. Muscle Nerve. 2015 Dec;52(6):1102-6. doi: 10.1002/mus.24729. Epub 2015 Jul 2. PubMed PMID: 26044970.

• Bensoussan L, Jouvion A, Kerzoncuf M, Delarque A, Theodoridou E, Milhe de Bovis V, Thefenne L, Attarian S, Viton JM. Orthopaedic shoes along with physical therapy was effective in Charcot-Marie-Tooth patient over 10 years. Prosthet Orthot Int. 2016 Oct;40(5):636-42. doi: 10.1177/0309364615584657. Epub 2015 May 26. PubMed PMID: 26015326.

• Morizot-Koutlidis R, André-Obadia N, Antoine JC, Attarian S, Ayache SS, Azabou E, Benaderette S, Camdessanché JP, Cassereau J, Convers P, d'Anglejean J, Delval A, Durand MC, Etard O, Fayet G, Fournier E, Franques J, Gavaret M, Guehl D, Guerit JM, Krim E, Kubis N, Lacour A, Lozeron P, Mauguière F, Merle PE, Mesrati F, Mutschler V, Nicolas G, Nordine T, Pautot V, Péréon Y, Petiot P, Pouget J, Praline J, Salhi H, Trébuchon A, Tyvaert L, Vial C, Zola JM, Zyss J, Lefaucheur JP. Somatosensory evoked potentials in the assessment of peripheral neuropathies: Commented results of a survey among French-speaking practitioners and recommendations for practice. Neurophysiol Clin. 2015 May;45(2):131-42. doi: 10.1016/j.neucli.2015.04.001. Epub 2015 May 6. PubMed PMID: 25957985.

• Sevy A, Cerino M, Gorokhova S, Dionnet E, Mathieu Y, Verschueren A, Franques J, Maues de Paula A, Figarella-Branger D, Lagarde A, Desvignes JP, Béroud C, Attarian S, Levy N, Bartoli M, Krahn M, Campana-Salort E, Pouget J. Improving molecular diagnosis of distal myopathies by targeted next-generation sequencing. J Neurol Neurosurg Psychiatry. 2016 Mar;87(3):340-2. doi: 10.1136/jnnp-2014-309663. Epub 2015 Mar 17. PubMed PMID: 25783436.

• Gesquière-Dando A, Attarian S, Maues De Paula A, Pouget J, Salort-Campana E. Fibromyalgia-like symptoms associated with irritable bowel syndrome: A challenging diagnosis of late-onset Pompe disease. Muscle Nerve. 2015 Aug;52(2):300-4. doi: 10.1002/mus.24618. Epub 2015 Jun 18. PubMed PMID: 25703594. 

• Ribot-Ciscar E, Milhe-De Bovis V, Aimonetti JM, Lapeyssonnie B, Campana-Salort E, Pouget J, Attarian S. Functional impact of vibratory proprioceptive assistance in patients with facioscapulohumeral muscular dystrophy. Muscle Nerve. 2015 Nov;52(5):780-7. doi: 10.1002/mus.24605. Epub 2015 Sep 3. PubMed PMID: 25678042.

• Puppo F, Dionnet E, Gaillard MC, Gaildrat P, Castro C, Vovan C, Bertaux K, Bernard R, Attarian S, Goto K, Nishino I, Hayashi Y, Magdinier F, Krahn M, Helmbacher F, Bartoli M, Lévy N. Identification of variants in the 4q35 gene FAT1 in patients with a facioscapulohumeral dystrophy-like phenotype. Hum Mutat. 2015 Apr;36(4):443-53. doi:  10.1002/humu.22760. Epub 2015 Mar 19. PubMed PMID: 25615407.

• Salort-Campana E, Nguyen K, Bernard R, Jouve E, Solé G, Nadaj-Pakleza A, Niederhauser J, Charles E, Ollagnon E, Bouhour F, Sacconi S, Echaniz-Laguna A, Desnuelle C, Tranchant C, Vial C, Magdinier F, Bartoli M, Arne-Bes MC, Ferrer X, Kuntzer T, Levy N, Pouget J, Attarian S. Low penetrance in facioscapulohumeral muscular dystrophy type 1 with large pathological D4Z4 alleles: a cross-sectional multicenter study. Orphanet J Rare Dis. 2015 Jan 21;10:2. doi: 10.1186/s13023-014-0218-1. PubMed PMID: 25603992; PubMed Central PMCID: PMC4320820.

• Attarian S, Franques J, Elisabeth J, Trébuchon A, Duclos Y, Wybrecht D, Verschueren A, Salort-Campana E, Pouget J. Triple-stimulation technique improves the diagnosis of chronic inflammatory demyelinating polyradiculoneuropathy. Muscle Nerve. 2015 Apr;51(4):541-8. doi: 10.1002/mus.24352. Epub 2015 Jan 9. PubMed PMID: 25571892.

• Attarian S, Vallat JM, Magy L, Funalot B, Gonnaud PM, Lacour A, Péréon Y, Dubourg O, Pouget J, Micallef J, Franques J, Lefebvre MN, Ghorab K, Al-Moussawi M, Tiffreau V, Preudhomme M, Magot A, Leclair-Visonneau L, Stojkovic T, Bossi L, Lehert P, Gilbert W, Bertrand V, Mandel J, Milet A, Hajj R, Boudiaf L, Scart-Grès C, Nabirotchkin S, Guedj M, Chumakov I, Cohen D. An exploratory randomised double-blind and placebo-controlled phase 2 study of a combination of baclofen, naltrexone and sorbitol (PXT3003) in patients with Charcot-Marie-Tooth disease type 1A. Orphanet J Rare Dis. 2014 Dec 18;9:199. doi: 10.1186/s13023-014-0199-0. Erratum in: Orphanet J Rare Dis. 2016;11(1):92. PubMed PMID: 25519680; PubMed Central PMCID: PMC4311411.

• Wakerley BR, Uncini A, Yuki N; GBS Classification Group; GBS Classification Group. Guillain-Barré and Miller Fisher syndromes--new diagnostic classification. Nat Rev Neurol. 2014 Sep;10(9):537-44. doi: 10.1038/nrneurol.2014.138. Epub 2014 Jul 29. Review. Erratum in: Nat Rev Neurol. 2014 Nov;10(11):612. PubMed PMID: 25072194.

• Gaillard MC, Roche S, Dion C, Tasmadjian A, Bouget G, Salort-Campana E, Vovan C, Chaix C, Broucqsault N, Morere J, Puppo F, Bartoli M, Levy N, Bernard R, Attarian S, Nguyen K, Magdinier F. Differential DNA methylation of the D4Z4 repeat in patients with FSHD and asymptomatic carriers. Neurology. 2014 Aug 19;83(8):733-42. doi: 10.1212/WNL.0000000000000708. Epub 2014 Jul 16. PubMed PMID: 25031281.

• Attarian S, Tran LC, Moore A, Stanton G, Meyer E, Moore RP. The neurodevelopmental impact of neonatal morphine administration. Brain Sci. 2014 Apr 25;4(2):321-34. doi: 10.3390/brainsci4020321. PubMed PMID: 24961764; PubMed Central PMCID: PMC4101480.

• Lagarde S, Tabouret E, Matta M, Franques J, Attarian S, Pouget J, Maues De Paula A, Figarella-Branger D, Dory-Lautrec P, Chinot O, Barrié M. Primary neurolymphomatosis diagnosis and treatment: a retrospective study. J Neurol Sci. 2014 Jul 15;342(1-2):178-81. doi: 10.1016/j.jns.2014.04.030. Epub 2014 May 1. PubMed PMID: 24831985.

• Seguier J, Serratrice J, Lachaud A, Belenotti P, Benyamine A, Verschueren A, Boucraut J, Attarian S, Weiller PJ. [Abdominal pain in progressive encephalomyelitis with rigidity]. Rev Med Interne. 2015 Apr;36(4):283-6. doi: 10.1016/j.revmed.2013.12.019. Epub 2014 Jan 21. French. PubMed PMID: 24461686.

• Lenglet T, Lacomblez L, Abitbol JL, Ludolph A, Mora JS, Robberecht W, Shaw PJ, Pruss RM, Cuvier V, Meininger V; Mitotarget study group. A phase II-III trial of olesoxime in subjects with amyotrophic lateral sclerosis. Eur J Neurol. 2014 Mar;21(3):529-36. doi: 10.1111/ene.12344. Epub 2014 Jan 21. PubMed PMID: 24447620.

• Grapperon AM, Verschueren A, Duclos Y, Confort-Gouny S, Soulier E, Loundou AD, Guye M, Cozzone PJ, Pouget J, Ranjeva JP, Attarian S. Association between structural and functional corticospinal involvement in amyotrophic lateral sclerosis assessed by diffusion tensor MRI and triple stimulation technique. Muscle Nerve. 2014 Apr;49(4):551-7. doi: 10.1002/mus.23957. Epub 2014 Feb 26. PubMed PMID: 23873504.

Recherches :

Le Service de Neurophysiologie Clinique de l’APHM est associé à l’INSERM et à l’Université d’Aix-Marseille dans l’Unité Mixte de Recherche « Institut de Neurosciences des Systèmes, INS» (INSERM UMR 1106, Dir. Viktor Jirsa). L’équipe « Épilepsie » travaille sur la physiopathologie des épilepsies, et recherche de nouvelles formes de traitement à la fois sur le plan expérimental et sur les données humaines. (site internet : (http://ins.univ-amu.fr/).
L’équipe clinique est intégrée  à la Fédération Hospitalo-Universitaire "EPINEXT" (« Epilepsies and disorders of Neuronal Excitability »)  (Directeur : Pr F Bartolomei) labélisée récemment par l'Université Aix Marseille et dédiée à la recherche et la prise en charge des épilepsies. Il s'agit du plus important regroupement d'équipes de recherche (11 unités INSERM y sont associées) sur l'épilepsie. Pour plus d'infos: http://www.epinext.org/

Publications : Exemples de publications récentes du service en Epileptologie
 
Bartolomei F, Trébuchon A, Bonini F, Lambert I, Gavaret M, Woodman M, Giusiano
B, Wendling F, Bénar C. What is the concordance between the seizure onset zone
and the irritative zone? A SEEG quantified study. Clin Neurophysiol. 2015 Oct 19.
pii: S1388-2457(15)00982-7. doi: 10.1016/j.clinph.2015.10.029. [Epub ahead of
print] PubMed PMID: 26520456.
 
Guerrini R, Duchowny M, Jayakar P, Krsek P, Kahane P, Tassi L, Melani F,
Polster T, Andre VM, Cepeda C, Krueger DA, Cross JH, Spreafico R, Cosottini M,
Gotman J, Chassoux F, Ryvlin P, Bartolomei F, Bernasconi A, Stefan H, Miller I,
Devaux B, Najm I, Giordano F, Vonck K, Barba C, Blumcke I. Diagnostic methods and
treatment options for focal cortical dysplasia. Epilepsia. 2015
Nov;56(11):1669-86. doi: 10.1111/epi.13200. Epub 2015 Oct 5. Review. PubMed PMID:
26434565.
 
 
Evangelista E, Bénar C, Bonini F, Carron R, Colombet B, Régis J, Bartolomei F.
Does the Thalamo-Cortical Synchrony Play a Role in Seizure Termination? Front
Neurol. 2015 Sep 1;6:192. doi: 10.3389/fneur.2015.00192. eCollection 2015. PubMed
PMID: 26388834; PubMed Central PMCID: PMC4555023.
 
Alexandre V, Mercedes B, Valton L, Maillard L, Bartolomei F, Szurhaj W, Hirsch
E, Marchal C, Chassoux F, Petit J, Crespel A, Nica A, Navarro V, Kahane P, De
Toffol B, Thomas P, Rosenberg S, Denuelle M, Jonas J, Ryvlin P, Rheims S;
REPO2MSE study group. Risk factors of postictal generalized EEG suppression in
generalized convulsive seizures. Neurology. 2015 Nov 3;85(18):1598-603. doi:
10.1212/WNL.0000000000001949. Epub 2015 Sep 2. PubMed PMID: 26333799.
 
Garbelli R, de Bock F, Medici V, Rousset MC, Villani F, Boussadia B,
Arango-Lievano M, Jeanneteau F, Daneman R, Bartolomei F, Marchi N. PDGFRβ(+)
cells in human and experimental neuro-vascular dysplasia and seizures.
Neuroscience. 2015 Oct 15;306:18-27. doi: 10.1016/j.neuroscience.2015.07.090.
Epub 2015 Aug 15. PubMed PMID: 26283024.
 
 
Muldoon SF, Villette V, Tressard T, Malvache A, Reichinnek S, Bartolomei F,
Cossart R. GABAergic inhibition shapes interictal dynamics in awake epileptic
mice. Brain. 2015 Oct;138(Pt 10):2875-90. doi: 10.1093/brain/awv227. Epub 2015
Aug 13. PubMed PMID: 26280596.
 
Badier JM, Bénar CG, Woodman M, Cruto C, Chauvel P, Bartolomei F, Gavaret M.
Ictal Magnetic Source Imaging in Presurgical Assessment. Brain Topogr. 2015 Aug
12. [Epub ahead of print] PubMed PMID: 26264375.
 
 
Bodin C, Aubert S, Daquin G, Carron R, Scavarda D, McGonigal A, Bartolomei F.
Responders to vagus nerve stimulation (VNS) in refractory epilepsy have reduced
interictal cortical synchronicity on scalp EEG. Epilepsy Res. 2015
Jul;113:98-103. doi: 10.1016/j.eplepsyres.2015.03.018. Epub 2015 Apr 9. PubMed
PMID: 25986196.
 
Bonini F, Lambert I, Wendling F, McGonigal A, Bartolomei F. Altered synchrony
and loss of consciousness during frontal lobe seizures. Clin Neurophysiol. 2015
Apr 15. pii: S1388-2457(15)00286-2. doi: 10.1016/j.clinph.2015.04.050. [Epub
ahead of print] PubMed PMID: 25912335.
 
 
Becker C, Bouvier E, Ghestem A, Siyoucef S, Claverie D, Camus F, Bartolomei
F, Benoliel JJ, Bernard C. Predicting and treating stress-induced vulnerability
to epilepsy and depression. Ann Neurol. 2015 Jul;78(1):128-36. doi:
10.1002/ana.24414. Epub 2015 May 25. PubMed PMID: 25869354.
Wendling F, Benquet P, Bartolomei F, Jirsa V. Computational models of
epileptiform activity. J Neurosci Methods. 2015 Apr 3. pii:
S0165-0270(15)00122-3. doi: 10.1016/j.jneumeth.2015.03.027. [Epub ahead of print]
Review. PubMed PMID: 25843066.
Guedj E, Bonini F, Gavaret M, Trébuchon A, Aubert S, Boucekine M, Boyer L,
Carron R, McGonigal A, Bartolomei F. 18FDG-PET in different subtypes of temporal
lobe epilepsy: SEEG validation and predictive value. Epilepsia. 2015
Mar;56(3):414-21. doi: 10.1111/epi.12917. Epub 2015 Feb 23. PubMed PMID:
25708545.
Jehi L, Yardi R, Chagin K, Tassi L, Russo GL, Worrell G, Hu W, Cendes F,
Morita M, Bartolomei F, Chauvel P, Najm I, Gonzalez-Martinez J, Bingaman W,
Kattan MW. Development and validation of nomograms to provide individualised
predictions of seizure outcomes after epilepsy surgery: a retrospective analysis.
Lancet Neurol. 2015 Mar;14(3):283-90. doi: 10.1016/S1474-4422(14)70325-4. Epub
2015 Jan 29. PubMed PMID: 25638640.
Micoulaud-Franchi JA, Barkate G, Trébuchon-Da Fonseca A, Vaugier L, Gavaret
M, Bartolomei F, McGonigal A. One step closer to a global tool for rapid
screening of major depression in epilepsy: validation of the French NDDI-E.
Epilepsy Behav. 2015 Mar;44:11-6. doi: 10.1016/j.yebeh.2014.12.011. Epub 2015 Jan
16. PubMed PMID: 25597527.
 
 
Arthuis M, Micoulaud-Franchi JA, Bartolomei F, McGonigal A, Guedj E. Resting
cortical PET metabolic changes in psychogenic non-epileptic seizures (PNES). J
Neurol Neurosurg Psychiatry. 2015 Oct;86(10):1106-12. doi:
10.1136/jnnp-2014-309390. Epub 2014 Dec 2. PubMed PMID: 25466258.
 
Micoulaud-Franchi JA, Kotwas I, Lanteaume L, Berthet C, Bastien M, Vion-Dury
J, McGonigal A, Bartolomei F. Skin conductance biofeedback training in adults
with drug-resistant temporal lobe epilepsy and stress-triggered seizures: a
proof-of-concept study. Epilepsy Behav. 2014 Dec;41:244-50. doi:
10.1016/j.yebeh.2014.10.017. Epub 2014 Nov 5. PubMed PMID: 25461224.
Proix T, Bartolomei F, Chauvel P, Bernard C, Jirsa VK. Permittivity coupling
across brain regions determines seizure recruitment in partial epilepsy. J
Neurosci. 2014 Nov 5;34(45):15009-21. doi: 10.1523/JNEUROSCI.1570-14.2014. PubMed
PMID: 25378166.
McGonigal A, Bartolomei F, Gavaret M, Chauvel P, Régis J. Gamma knife
radiosurgery of paracentral epilepsy. Stereotact Funct Neurosurg.
2014;92(6):346-53. doi: 10.1159/000364915. Epub 2014 Oct 28. PubMed PMID:
25358847.
Badier JM, Bartolomei F, Chauvel P, Bénar CG, Gavaret M. Magnetic source
imaging in posterior cortex epilepsies. Brain Topogr. 2015 Jan;28(1):162-71. doi:
10.1007/s10548-014-0412-4. Epub 2014 Oct 29. PubMed PMID: 25352165.
 
de la Vaissière S, Milh M, Scavarda D, Carron R, Lépine A, Trébuchon A,
Gavaret M, Hewett R, Laguitton V, Daquin G, Villeneuve N, Bartolomei F. Cortical
involvement in focal epilepsies with epileptic spasms. Epilepsy Res. 2014
Nov;108(9):1572-80. doi: 10.1016/j.eplepsyres.2014.08.008. Epub 2014 Aug 30.
PubMed PMID: 25212728.
 
Koubeissi MZ, Bartolomei F, Beltagy A, Picard F. Electrical stimulation of a
small brain area reversibly disrupts consciousness. Epilepsy Behav. 2014
Aug;37:32-5. doi: 10.1016/j.yebeh.2014.05.027. Epub 2014 Jun 24. PubMed PMID:
24967698.
Sevy A, Gavaret M, Trebuchon A, Vaugier L, Wendling F, Carron R, Regis J,
Chauvel P, Gonigal AM, Bartolomei F. Beyond the lesion: the epileptogenic
networks around cavernous angiomas. Epilepsy Res. 2014 May;108(4):701-8. doi:
10.1016/j.eplepsyres.2014.02.018. Epub 2014 Mar 12. PubMed PMID: 24661427.
Mosbah A, Tramoni E, Guedj E, Aubert S, Daquin G, Ceccaldi M, Félician O,
Bartolomei F. Clinical, neuropsychological, and metabolic characteristics of
transient epileptic amnesia syndrome. Epilepsia. 2014 May;55(5):699-706. doi:
10.1111/epi.12565. Epub 2014 Mar 1. PubMed PMID: 24580051.
Micoulaud-Franchi JA, Lanteaume L, Pallanca O, Vion-Dury J, Bartolomei F.
[Biofeedback and drug-resistant epilepsy: back to an earlier treatment?]. Rev
Neurol (Paris). 2014 Mar;170(3):187-96. doi: 10.1016/j.neurol.2013.10.011. Epub
2014 Feb 24. Review. French. PubMed PMID: 24576530.
McGonigal A, Bartolomei F. Parietal seizures mimicking psychogenic
nonepileptic seizures. Epilepsia. 2014 Jan;55(1):196-7. doi: 10.1111/epi.12465.
PubMed PMID: 24446959.
 
Bonini F, McGonigal A, Trébuchon A, Gavaret M, Bartolomei F, Giusiano B,
Chauvel P. Frontal lobe seizures: from clinical semiology to localization.
Epilepsia. 2014 Feb;55(2):264-77. doi: 10.1111/epi.12490. Epub 2013 Dec 24.
PubMed PMID: 24372328.
 
Hewett R, Bartolomei F. Epilepsy and the cortical vestibular system: tales of
dizziness and recent concepts. Front Integr Neurosci. 2013 Nov 11;7:73. doi:
10.3389/fnint.2013.00073. eCollection 2013. Review. PubMed PMID: 24273498; PubMed
Central PMCID: PMC3822407.
 
Malinowska U, Badier JM, Gavaret M, Bartolomei F, Chauvel P, Bénar CG.
Interictal networks in magnetoencephalography. Hum Brain Mapp. 2014
Jun;35(6):2789-805. doi: 10.1002/hbm.22367. Epub 2013 Sep 18. PubMed PMID:
24105895.
 
Bartolomei F, McGonigal A, Naccache L. Alteration of consciousness in focal
epilepsy: the global workspace alteration theory. Epilepsy Behav. 2014
Jan;30:17-23. doi: 10.1016/j.yebeh.2013.09.012. Epub 2013 Oct 6. Review. PubMed
PMID: 24103816.
 
Trebuchon A, Bartolomei F, McGonigal A, Laguitton V, Chauvel P. Reversible
antisocial behavior in ventromedial prefrontal lobe epilepsy. Epilepsy Behav.
2013 Nov;29(2):367-73. doi: 10.1016/j.yebeh.2013.08.007. Epub 2013 Sep 24. PubMed
PMID: 24074892.
 
Picard F, Scavarda D, Bartolomei F. Induction of a sense of bliss by
electrical stimulation of the anterior insula. Cortex. 2013
Nov-Dec;49(10):2935-7. doi: 10.1016/j.cortex.2013.08.013. Epub 2013 Sep 3. PubMed
PMID: 24074887.
Gavaret M, Badier JM, Bartolomei F, Bénar CG, Chauvel P. MEG and EEG
sensitivity in a case of medial occipital epilepsy. Brain Topogr. 2014
Jan;27(1):192-6. doi: 10.1007/s10548-013-0317-7. Epub 2013 Sep 5. PubMed PMID:
24005334.
 
Bartolomei F, Bettus G, Stam CJ, Guye M. Interictal network properties in
mesial temporal lobe epilepsy: a graph theoretical study from intracerebral
recordings. Clin Neurophysiol. 2013 Dec;124(12):2345-53. doi:
10.1016/j.clinph.2013.06.003. Epub 2013 Jun 28. PubMed PMID: 23810635.
 
Bonini F, McGonigal A, Wendling F, Régis J, Scavarda D, Carron R, Chauvel P,
Bartolomei F. Epileptogenic networks in seizures arising from motor systems.
Epilepsy Res. 2013 Sep;106(1-2):92-102. doi: 10.1016/j.eplepsyres.2013.04.011.
Epub 2013 May 30. PubMed PMID: 23726290.
 
Blümcke I, Thom M, Aronica E, Armstrong DD, Bartolomei F, Bernasconi A,
Bernasconi N, Bien CG, Cendes F, Coras R, Cross JH, Jacques TS, Kahane P, Mathern
GW, Miyata H, Moshé SL, Oz B, Özkara Ç, Perucca E, Sisodiya S, Wiebe S, Spreafico
R. International consensus classification of hippocampal sclerosis in temporal
lobe epilepsy: a Task Force report from the ILAE Commission on Diagnostic
Methods. Epilepsia. 2013 Jul;54(7):1315-29. doi: 10.1111/epi.12220. Epub 2013 May
20. PubMed PMID: 23692496.
 
Lambert I, Arthuis M, McGonigal A, Wendling F, Bartolomei F. Alteration of
global workspace during loss of consciousness: a study of parietal seizures.
Epilepsia. 2012 Dec;53(12):2104-10. doi: 10.1111/j.1528-1167.2012.03690.x. Epub
2012 Sep 27. PubMed PMID: 23016829.
Chauvière L, Doublet T, Ghestem A, Siyoucef SS, Wendling F, Huys R, Jirsa V,
Bartolomei F, Bernard C. Changes in interictal spike features precede the onset
of temporal lobe epilepsy. Ann Neurol. 2012 Jun;71(6):805-14. doi:
10.1002/ana.23549. PubMed PMID: 22718546.
 
 
Guedj E, McGonigal A, Vaugier L, Mundler O, Bartolomei F. Metabolic brain PET
pattern underlying hyperkinetic seizures. Epilepsy Res. 2012 Sep;101(3):237-45.
doi: 10.1016/j.eplepsyres.2012.04.008. Epub 2012 May 1. PubMed PMID: 22551665.
 
Lanteaume L, Guedj E, Bastien-Toniazzo M, Magalahaes A, Mundler O, Bartolomei
F. Cognitive and metabolic correlates of emotional vulnerability in patients with
temporal lobe epilepsy. J Neurol Neurosurg Psychiatry. 2012 May;83(5):522-8. doi:
10.1136/jnnp-2011-301219. Epub 2012 Jan 31. PubMed

Publications :

• Liver transplantation for primary or secondary endocrine tumors. E GREGOIRE, YP LE TREUT Transplant Int 2010, 23:704-11
• Surgery for hilar cholangiocarcinoma: A multi-institutional update on practice and outcome by the AFC-HC Study Group.! JM REGIMBEAU, D FUKS, YP LE TREUT, P BACHELLIER, J BELGHITI, K BOUDJEMA, J BAULIEUX, FR PRUVOT, D CHERQUI, O FARGES. J Gastrointest Surg 2011, 15:480-8
• Pancreatic head resectable adenocarcinoma: preoperative chemoradiation improves local control but does not affect survival. L BARBIER, O TURRINI, E GREGOIRE, F VIRET, YP LE TREUT, JR DELPERO. HPB Surg 2011, 13: 64-69
• Prognostic value of jaundice in patients with gallbladder cancer by the AFC-GBC- 2009 study group. JM REGIMBEAU, D FUKS, P BACHELLIER, YP LE TREUT, FR PRUVOT, F NAVARRO, L CHICHE, O FARGES. Eur J Surg Oncol 2011, 37: 505-12
• Incidental gallbladder cancer by the AFC-GBC-2009 study group. D FUKS, JM REGIMBEAU, YP LE TREUT, P BACHELLIER, A RAVENTOS, FR PRUVOT, L CHICHE, O FARGES. World J Surg 2011, 35: 1887-97
• Liver transplantation for unresectable hepatocellular carcinoma in normal liver. H MERGENTAL, R ADAM, BG ERICZON, P KALINCINSKI, F MUHLBACHER, K HOCKERSTEDT, JL KLEMPNAUER, S FRIMAN, C BROELSCH, G MANTION, C FERNANDEZ-SELLEZ, B VAN HOEK, J FANGMANN, J PIRENNE, P MUIESAN, A KONINGSRIDER, D MIRZA, J LERUT, O DETRY, YP LE TREUT, V MAZZAFERRO, F LOHE, M BERENGUER, PA CLAVIEN, X ROGIERS, J BELGHITI, L KOBORI, P BURRA, P WOLF, W SCHAREK, P PISARSKI, A FOSS, F FILIPPONI, M KRAWCZYK, M WOLFF, JM LANGREHR, K ROLLES, N JAMIESON, WCJ HOP, RJ PORTE for the European Liver and Intestine Transplant Association (ELITA). J Hepatol 2012, 57:297-305
• Is hepatic resection the best treatment for hydatid cyst? DJ BIRNBAUM, J HARDWIGSEN, L BARBIER, N BOUCHIBA, YP LE TREUT J Gastrointest Surg 2012, 16:2086-93
• Multicentre European study of preoperative biliary drainage for hilar cholangiocarcinoma. O FARGES, JM REGIMBEAU, D FUKS, YP LE TREUT, D CHERQUI, P BACHELLIER, JY MABRUT, M ADHAM, FR PRUVOT, JF GIGOT. Br J Surg 2013, 100: 274-83
• Liver transplantation for neuroendocrine tumors in Europe - Results and trends in patient selection. A 213-case European Liver Transplantation Registry study. YP Le Treut, E Grégoire, J Klempnauer, J Belghiti , E Jouve, J Lerut, D Castaing, O Soubrane, O Boillot, G Mantion, K Homayounfar, M Bustamente, D Azoulay, Ph Wolf, M Krawczyk, A Pascher, B Suc, L Chiche, J Ortiz de UrbinA, V Mejzlik, M Pascual, JPA Lodge, S Gruttadauria, F Paye, FR Pruvot, S Thorban, A Foss, R Adam, for ELITA. Ann Surg 2013, 257: 807-15
• Assessment of late chronic rejection in liver graft recipients receiving immunosuppression with low-dose calcineurin inhibitors. L BARBIER, S GARCIA, J CROS, P BORENTAIN, D BOTTA-FRIDLUND, V PARADIS, YP LE TREUT, J HARDWIGSEN J Hepatol 2013, 59:1223-30
• Transdiaphragmatic extrapericardial approach of the inferior vena cava. YP LE TREUT, R FARA, L BARBIER, JR DELPERO, N ARELLANO, J HARDWIGSEN. J Am Coll Surg 2013, 217: 41-3
• Pancreaticoduodenectomy for pancreatic ductal adenocarcinoma: results of French prospective multicentric evaluation of the margins of resection in 150 evaluable specimens. JR DELPERO, P BACHELLIER, N REGENET, YP LE TREUT, F PAYE, N CARRERE, A AUTRET, O TURRINI, G MONGES-RANCHIN, JM BOHER. HPB (Oxford) 2014, 16: 20-33
• Lymphoepithelial cyst of the pancreas: an analysis of 117 patients. D MEGE, E GREGOIRE, L BARBIER, J DEL GRANDE, YP LE TREUT. Pancreas 2014, 43: 987-95
• Minimal portal vein stenosis trigger contralateral liver hypertrophy whitout downstream atrophy in a porcine model for living donor preconditioning. E GREGOIRE, P BRIGGE, L BARBIER, C BUFFAT, A COPPOLA, J HARDWIGSEN, YP LE TREUT, V VIDAL, PH ROLLAND. J Hepatol 2014, 61: 59-66
• Giant renal angiomyolipoma with right heart failure R LE HUU NHO, S RENARD, C MAURIN, P SOUTEYRAND, YP LE TREUT Prog Urol 2014, 24 : 479-81
• How relevant is peak postoperative cytolysis after an elective hepatectomy? E BOLESLAWSKI, E VIBERT, FR PRUVOT, YP LE TREUT, O SCATTON, C LAURENT, JY MABRUT, JM REGIMBEAU, M ADHAM, C COSSE, O FARGES Ann Surg 2014, 260: 815-821
• “Intuition” versus “evidence”: predicting the risk of liver resections. O FARGES, E VIBERT, C COSSE, FR PRUVOT, YP LE TREUT, O SCATTON, C LAURENT, JY MABRUT, JM REGIMBEAU, M ADHAM, B FAISSARD, E BOLESLAWSKI Ann Surg 2014, 260: 923-930
• Liver transplantation for neuroendocrine tumour liver metastases ST FAN, YP LE TREUT, V MAZZAFERRO, AK BURROUGH, M OLAUSSON, S BRETENSTEIN, A FRILLING HBP Surg (Oxford) 2015, 17:23-8
• Tumour size over 3 cm predicts poor outcomes after major liver resection for hilar cholangiocarcinoma. By the HC-AFC-2009 group. JM REGIMBEAU, D FUKS, P PESSAUX, P BACHELLIER, D CHATELAIN, M DIOUF, A RAVENTOS, G MANTION, JF GIGOT, L CHICHE, G PASCAL, D AZOULAY, A LAURENT, C LETOUBLON, E BOLESLAWSKI, M RIVOIRE, JY MABRUT, M ADHAM, YP LE TREUT, JR DELPERO, F NAVARRO, A AYAV, K BOUDJEMA, G NUZZO, M SCOTTE, O FARGES.
• HPB Surg (Oxford) 2015, 17:79-86
• Pancreatic adenocarcinoma with venous involvement : is up-front synchronous portal-mesenteric vein resection still justified ? A survey of the « Association Française de Chirurgie ». JR DELPERO, JM BOHER, A SAUVANET, YP LE TREUT, A SA CUNHA, JY MABRUT, L CHICHE, O TURRINI, P BACHELLIER, F PAYE. Ann Surg Oncol 2015 (sous presse)
• Patients with acute liver failure listed for super-urgent liver transplantation in France: Outcome and evaluation of the Clichy-Villejuif criteria. P ICHAI, C LEGEAI, C FRANCOZ, K BOUDJEMA, O BOILLOT, C DUCERF, P MATHURIN, B Suc, P Wolf, F-R Pruvot, O Soubrane, YP Le Treut, D Azoulay, L Hannoun, G-P Pageaux, J Gugenheim, C Letoublon, J Saric, V Di Martino, J Chipponi, L Chiche, C Antoine, D Castaing, D Samuel and French Liver Transplant Teams. Liver Transplant  2015 (sous presse). 

Recherches :

• Cancers primitifs du foie : scores pronostiques
• Coût et risque des hépatectomies
• Modulation du flux portal
• Transplantation pour tumeurs endocrines
• Immunosuppression en transplantation hépatique

• Chirurgie de la main vasculaire
• Algodystrophie
• Thérapie cellulaire
• Arthrose du poignet
• Régénération des nerfs périphériques
• Vitamine D, nerfs périphériques
• Prothèses main
• Toxine Botulinique
• Rééducation poprioceptive, illusion mouvement
• Biomécanique de la main
• Pathologies congénitales de la main